Yang Ao, Zhang Cong, Zhang Beiyu, Wang Zhiyun, Zhu Luoyi, Mu Yang, Wang Shuai, Qi Desheng
Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China.
Animals (Basel). 2021 Jan 4;11(1):78. doi: 10.3390/ani11010078.
Antinutrients, such as cyclopropene fatty acids (CPFAs) and free gossypol (FG), present together in cottonseed have caused numerous adverse effects on liver health and egg quality of laying hens, which are both likely to be related to a disturbance in lipid metabolism. This experiment employed a 3 × 3 factorial arrangement using corn-soybean-meal-based diets supplemented with different levels of cottonseed oil (0%, 2%, or 4% CSO) containing CPFAs and cottonseed meal (0%, 6%, or 12% CSM) containing FG to elucidate the effects of them or their interaction on fatty acid profile, lipid content, and liver health of laying hens. An overall increase in fatty acid saturation and an overall significant decrease ( < 0.05) in monounsaturated fatty acids (MUFAs) were shown in the livers of hens fed diets with either 2% or 4% CSO. Meanwhile, the concentration of liver cholesterol, serum cholesterol, and serum LDL-c of hens fed a diet supplemented with a high level of CSO (4%) were noticeably increased ( < 0.05). Even though the supplementation of 4% CSO in diets aroused beneficial influences on liver function, a high level of CSO inclusion in laying hens' diets is not recommended due to its hypercholesterolemia effect. In conclusion, supplementation of CSO, which contains 0.20% CPFAs, was the primary cause of alteration in fatty acid composition and cholesterol content in hens, while no interaction between CSM and CSO nor CSM effect was found for lipid profile and liver health in laying hen.
抗营养因子，如环丙烯脂肪酸（CPFAs）和游离棉酚（FG），同时存在于棉籽中，已对蛋鸡的肝脏健康和蛋品质造成了诸多不利影响，这两者都可能与脂质代谢紊乱有关。本实验采用3×3析因设计，以玉米-豆粕型日粮为基础，添加不同水平含CPFAs的棉籽油（0%、2%或4% CSO）和含FG的棉籽粕（0%、6%或12% CSM），以阐明它们或其相互作用对蛋鸡脂肪酸谱、脂质含量和肝脏健康的影响。饲喂含2%或4% CSO日粮的母鸡肝脏中，脂肪酸饱和度总体增加，单不饱和脂肪酸（MUFAs）总体显著降低（<0.05）。同时，饲喂添加高水平CSO（4%）日粮的母鸡肝脏胆固醇、血清胆固醇和血清低密度脂蛋白胆固醇浓度显著升高（<0.05）。尽管日粮中添加4% CSO对肝功能有有益影响，但由于其高胆固醇血症效应，不建议在蛋鸡日粮中高水平添加CSO。总之，添加含0.20% CPFAs的CSO是母鸡脂肪酸组成和胆固醇含量改变的主要原因，而未发现CSM和CSO之间存在相互作用，也未发现CSM对蛋鸡脂质谱和肝脏健康有影响。
