Department of Ear, Nose and Throat Diseases, Yenimahalle Education and Research Hospital, Ankara Yıldırım Beyazıt University, Ankara.
Department of Ear, Nose and Throat Diseases, Istanbul Kartal Dr Lutfi Kirdar Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
J Laryngol Otol. 2021 Jan;135(1):45-49. doi: 10.1017/S0022215120002765. Epub 2021 Jan 7.
This study aimed to evaluate the association between serum D-dimer, ferritin and vitamin D levels, and dysgeusia symptoms, in patients with coronavirus disease 2019.
The present study was conducted with the medical records of 300 patients positive for coronavirus disease 2019, hospitalised between 28 March and 15 August 2020. The patients were divided into two groups regarding the presence or absence of dysgeusia symptoms.
Fever and sore throat rates, and the mean D-dimer level, were considerably higher in the dysgeusia group than in the non-dysgeusia group (32.1 vs 21.6 per cent, p = 0.04; 43.6 vs 20.7 per cent, p < 0.001; and 0.54 ± 0.32 vs 0.49 ± 0.51 mg/l FEU, p = 0.008, respectively). The mean age was significantly lower in the dysgeusia group than in the non-dysgeusia group (42.83 ± 12.31 vs 50.51 ± 13.67 years, p < 0.001).
Younger age, fever and shortness of breath could be observed in patients with dysgeusia symptoms. In addition, the D-dimer level was significantly higher in the dysgeusia group.
本研究旨在评估血清 D-二聚体、铁蛋白和维生素 D 水平与 COVID-19 患者味觉障碍症状之间的关系。
本研究纳入了 2020 年 3 月 28 日至 8 月 15 日期间 300 例 COVID-19 阳性住院患者的病历。根据是否存在味觉障碍症状将患者分为两组。
味觉障碍组的发热和咽痛发生率以及平均 D-二聚体水平明显高于无味觉障碍组（32.1%比 21.6%，p=0.04；43.6%比 20.7%，p<0.001；0.54±0.32 mg/l FEU 比 0.49±0.51 mg/l FEU，p=0.008）。味觉障碍组的平均年龄明显低于无味觉障碍组（42.83±12.31 岁比 50.51±13.67 岁，p<0.001）。
味觉障碍患者可能出现年龄较小、发热和呼吸急促的症状，此外，味觉障碍组的 D-二聚体水平明显更高。
