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一名继发于新型冠状病毒肺炎感染的过敏性紫癜患儿。

A child with Henoch-Schonlein purpura secondary to a COVID-19 infection.

作者信息

AlGhoozi Dalal Anwar, AlKhayyat Haya Mohammed

机构信息

Pediatrics, Bahrain Defence Force Royal Medical Services, Riffa, Bahrain

Pediatrics, Bahrain Defence Force Royal Medical Services, Riffa, Bahrain.

出版信息

BMJ Case Rep. 2021 Jan 6;14(1):e239910. doi: 10.1136/bcr-2020-239910.

Abstract

Henoch-Schonlein purpura (HSP) is a common IgA-mediated small vessel vasculitis of childhood that affects several systems. It is characterised by a tetrad of dermatological, abdominal, joint and renal manifestations. HSP can occur secondary to upper respiratory tract infections, medications, vaccinations and malignancies. COVID-19 is caused by SARS-CoV-2, a single-stranded RNA virus from the Beta-Coronaviridae family, and often presents as a respiratory infection with symptoms ranging from a mild common cold-like illness to severe pneumonia. It has also been reported to exhibit extrapulmonary manifestations, including but not limited to cardiac, thrombotic, hepatocellular and dermatological complications. We report a case of a 4-year-old boy who presented with clinical features of HSP, with detailed history that revealed a recent recovery from a COVID-19 upper respiratory tract infection, indicating a possible correlation between the two.

摘要

过敏性紫癜(HSP)是一种常见的儿童IgA介导的小血管血管炎,可累及多个系统。其特征为皮肤、腹部、关节和肾脏表现四联征。HSP可继发于上呼吸道感染、药物、疫苗接种和恶性肿瘤。新型冠状病毒肺炎(COVID-19)由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起,SARS-CoV-2是一种来自β冠状病毒科的单链RNA病毒,通常表现为呼吸道感染,症状从轻度感冒样疾病到严重肺炎不等。也有报道称其可出现肺外表现,包括但不限于心脏、血栓形成、肝细胞和皮肤并发症。我们报告一例4岁男孩,其表现出HSP的临床特征,详细病史显示其近期从COVID-19上呼吸道感染中康复,提示两者之间可能存在关联。

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