AlGhoozi Dalal Anwar, AlKhayyat Haya Mohammed
Pediatrics, Bahrain Defence Force Royal Medical Services, Riffa, Bahrain
Pediatrics, Bahrain Defence Force Royal Medical Services, Riffa, Bahrain.
BMJ Case Rep. 2021 Jan 6;14(1):e239910. doi: 10.1136/bcr-2020-239910.
Henoch-Schonlein purpura (HSP) is a common IgA-mediated small vessel vasculitis of childhood that affects several systems. It is characterised by a tetrad of dermatological, abdominal, joint and renal manifestations. HSP can occur secondary to upper respiratory tract infections, medications, vaccinations and malignancies. COVID-19 is caused by SARS-CoV-2, a single-stranded RNA virus from the Beta-Coronaviridae family, and often presents as a respiratory infection with symptoms ranging from a mild common cold-like illness to severe pneumonia. It has also been reported to exhibit extrapulmonary manifestations, including but not limited to cardiac, thrombotic, hepatocellular and dermatological complications. We report a case of a 4-year-old boy who presented with clinical features of HSP, with detailed history that revealed a recent recovery from a COVID-19 upper respiratory tract infection, indicating a possible correlation between the two.
过敏性紫癜(HSP)是一种常见的儿童IgA介导的小血管血管炎,可累及多个系统。其特征为皮肤、腹部、关节和肾脏表现四联征。HSP可继发于上呼吸道感染、药物、疫苗接种和恶性肿瘤。新型冠状病毒肺炎(COVID-19)由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起,SARS-CoV-2是一种来自β冠状病毒科的单链RNA病毒,通常表现为呼吸道感染,症状从轻度感冒样疾病到严重肺炎不等。也有报道称其可出现肺外表现,包括但不限于心脏、血栓形成、肝细胞和皮肤并发症。我们报告一例4岁男孩,其表现出HSP的临床特征,详细病史显示其近期从COVID-19上呼吸道感染中康复,提示两者之间可能存在关联。