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Hydroxychloroquine as a Chemoprophylactic Agent for COVID-19: A Clinico-Pharmacological Review.羟氯喹作为COVID-19的化学预防剂:临床药理学综述
Front Pharmacol. 2020 Dec 17;11:593099. doi: 10.3389/fphar.2020.593099. eCollection 2020.
2
Assessment of Preventive Practices Followed by General Public During COVID-19 Pandemic - A Cross-Sectional Survey From India.新冠疫情期间印度公众预防措施的评估——一项横断面调查
Cureus. 2020 Oct 31;12(10):e11274. doi: 10.7759/cureus.11274.
3
Use of hydroxychloroquine for pre-exposure prophylaxis in COVID 19: debate and suggested future course.羟氯喹用于2019冠状病毒病暴露前预防:争论与未来建议方向
Expert Rev Anti Infect Ther. 2021 Apr;19(4):413-417. doi: 10.1080/14787210.2021.1828062. Epub 2020 Oct 7.
4
A short questionnaire to assess changes in lifestyle-related behaviour during COVID 19 pandemic.评估 COVID-19 大流行期间与生活方式相关行为变化的简短问卷。
Diabetes Metab Syndr. 2020 Nov-Dec;14(6):1697-1701. doi: 10.1016/j.dsx.2020.08.020. Epub 2020 Aug 26.
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Cross-Country Comparison of Public Awareness, Rumors, and Behavioral Responses to the COVID-19 Epidemic: Infodemiology Study.新冠疫情公众认知、谣言及行为反应的跨国比较:信息流行病学研究
J Med Internet Res. 2020 Aug 3;22(8):e21143. doi: 10.2196/21143.
6
Endothelial dysfunction in Coronavirus disease 2019 (COVID-19): Gender and age influences.2019 年冠状病毒病(COVID-19)中的血管内皮功能障碍:性别和年龄的影响。
Med Hypotheses. 2020 Nov;144:110015. doi: 10.1016/j.mehy.2020.110015. Epub 2020 Jun 20.
7
Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis.物理隔离、口罩和眼部防护预防 SARS-CoV-2 和 COVID-19 的人际传播:系统评价和荟萃分析。
Lancet. 2020 Jun 27;395(10242):1973-1987. doi: 10.1016/S0140-6736(20)31142-9. Epub 2020 Jun 1.
8
AYUSH for COVID-19: Science or Superstition?阿育吠陀应对 COVID-19:科学还是迷信?
Indian J Public Health. 2020 Jun;64(Supplement):S105-S107. doi: 10.4103/ijph.IJPH_500_20.
9
Age-dependent Gender Differences in COVID-19 in Mainland China: Comparative Study.中国大陆 COVID-19 患者的年龄相关性别差异:比较研究。
Clin Infect Dis. 2020 Dec 3;71(9):2488-2494. doi: 10.1093/cid/ciaa683.
10
Gender and Age Differences Reveal Risk Patterns in COVID-19 Outbreak.性别和年龄差异揭示了新冠疫情中的风险模式。
Altern Ther Health Med. 2020 Aug;26(S2):54-55.

自我报告的预防措施依从性与新冠病毒检测呈阳性概率之间的关联:一项横断面分析研究。

Association Between Self-Reported Adherence to Preventive Practices and Probability of Turning COVID-19 Positive: A Cross-Sectional Analytical Study.

作者信息

Ranjan Piyush, Bhattacharya Aakashneel, Chakrawarty Avinash, Das Rojaleen, Kumar Arvind, Pandey Shivam, Chowdhury Souradeep, Mittal Ankit, Baitha Upendra, Wig Naveet

机构信息

Medicine, All India Institute of Medical Sciences, New Delhi, IND.

Infectious Diseases, All India Institute of Medical Sciences, New Delhi, IND.

出版信息

Cureus. 2020 Dec 1;12(12):e11815. doi: 10.7759/cureus.11815.

DOI:10.7759/cureus.11815
PMID:33409060
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7781500/
Abstract

Background Preventive practices are the mainstay to mitigate the spread of the COVID-19 pandemic. We tried to assess the self-reported adherence of our participants to the already known preventive practices. Furthermore, we tried to determine whether the non-compliance to specific preventive practices was associated with the acquisition of the infection or not. Methods We enrolled 379 healthcare workers, hospital staff, and their family members who were tested for COVID-19 by reverse transcription-polymerase chain reaction (RT-PCR) in an outpatient clinic. Socio-demography and the infection prevention practices of the individuals were recorded in a preformed questionnaire. Statistical analysis was performed to find out the statistical association between these factors and the RT-PCR results. Adjusted and unadjusted odds ratios were determined to find out the degree of protection provided by each of the preventive practices concerning the development of the disease. Results Social distancing (p<0.001), hand hygiene (p<0.001), ensuring N-95 mask fit check (p<0.001), and the use of alternative medications (p=0.002) were found to be protective. Resident doctors were at a lower risk of developing the disease as compared to the other healthcare workers (odds ratio: 0.39). Conclusion The failure to practice the already known preventive practices is probably one of the most important factors in the progression of the COVID-19 pandemic. Adherence to these practices is the intervention of choice to reduce disease transmission in the current scenario.

摘要

背景 预防措施是减轻新冠疫情传播的主要手段。我们试图评估参与者自我报告的对已知预防措施的遵守情况。此外,我们试图确定不遵守特定预防措施是否与感染的发生有关。方法 我们招募了379名医护人员、医院工作人员及其家属,他们在门诊通过逆转录聚合酶链反应(RT-PCR)进行了新冠病毒检测。在一份预先设计好的问卷中记录了个人的社会人口统计学信息和感染预防措施。进行统计分析以找出这些因素与RT-PCR结果之间的统计关联。确定调整和未调整的优势比,以找出每种预防措施对疾病发展提供的保护程度。结果 社交距离(p<0.001)、手部卫生(p<0.001)、确保N-95口罩贴合度检查(p<0.001)以及使用替代药物(p=0.002)被发现具有保护作用。与其他医护人员相比,住院医生患该病的风险较低(优势比:0.39)。结论 不践行已知的预防措施可能是新冠疫情蔓延的最重要因素之一。在当前情况下,遵守这些措施是减少疾病传播的首选干预措施。