Leuschner U, Hellstern A, Wendt T, Birkenfeld G, Leuschner M, Gatzen M, Kurtz W, Fischer H
Zentrum der Inneren Medizin, Johann Wolfgang Goethe-Universität, Frankfurt, FRG.
Am J Gastroenterol. 1988 Feb;83(2):169-72.
We report on a 36-yr-old woman with six gallstones measuring 2.1 cm each. Within 21 h of methyl-tert-butyl ether (MTBE) treatment, the stones had dissolved to a small amount of residue. As could be seen from cholesterol concentrations of samples of aspirated gallbladder bile and MTBE fractions, the dissolution process was slow to begin with, and gained momentum during hours 6-11, after which it decelerated. We discontinued treatment after 20 h, since the stone residue showed no change. Cholecystoscopy performed with an Edwards angioscope via a catheter showed that there were no stone remnants, but that there were flat polyps on the gallbladder wall. One hour later, we stopped the therapy. Cholecystoscopy is a useful method of assessing the results of MTBE treatment.
我们报告了一名36岁的女性,她有6颗胆囊结石,每颗结石直径为2.1厘米。在使用甲基叔丁基醚(MTBE)治疗的21小时内,结石溶解为少量残余物。从吸出的胆囊胆汁样本和MTBE组分的胆固醇浓度可以看出,溶解过程开始时较慢,在6至11小时期间加速,之后又减速。由于结石残余物没有变化,我们在20小时后停止了治疗。通过导管使用爱德华兹血管镜进行的胆囊镜检查显示没有结石残余,但胆囊壁上有扁平息肉。1小时后,我们停止了治疗。胆囊镜检查是评估MTBE治疗效果的一种有用方法。