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补充葡萄多酚对抗运动引起的氧化应激。

Grape polyphenols supplementation for exercise-induced oxidative stress.

机构信息

TECNALIA, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Álava c/ Leonardo Da Vinci, 11, 01510 Miñano (Álava), Spain.

Analytical Chemistry Department, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), P.O. Box 644, 48080, Bilbao, Spain.

出版信息

J Int Soc Sports Nutr. 2021 Jan 7;18(1):3. doi: 10.1186/s12970-020-00395-0.

DOI:10.1186/s12970-020-00395-0
PMID:33413451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7789302/
Abstract

Exercise induces free radicals' overproduction and therefore, an enhancement of oxidative stress, defined as an imbalance between the production of reactive species and the intrinsic antioxidant defense. Redox activity of reactive species plays an important and a positive role on exercise adaptation, but these species at very high concentrations have detrimental effects. As a result, the use of antioxidant supplements for reducing oxidative stress can be an effective health strategy to maintain an optimal antioxidant status. In this sense, grapes are an important source of natural antioxidants due to their high content in polyphenols. They have shown antioxidant potential benefits for the reduction of intense exercise effect in athletes of different sport disciplines. Consequently, it is plausible to hypothesize that a strategic supplementation with grape based products may be a good approach to mitigate the exercise induced oxidative stress. The goal of this review is to present the state of the art of supplementation effects with grape beverages and grape extracts on the oxidative stress markers in athletes. The data of polyphenolic dosages, participant characteristics and exercise protocols are reported.

摘要

运动导致自由基的过度产生,从而增强了氧化应激,氧化应激定义为活性物质的产生和内在抗氧化防御之间的失衡。活性物质的氧化还原活性对运动适应起着重要的积极作用,但这些物质在非常高的浓度下会产生有害影响。因此,使用抗氧化补充剂来降低氧化应激可能是维持最佳抗氧化状态的有效健康策略。在这方面,葡萄由于其多酚含量高,是天然抗氧化剂的重要来源。它们具有抗氧化的潜在益处,可以减少不同运动项目运动员剧烈运动的影响。因此,合理假设通过葡萄产品进行策略性补充可能是减轻运动引起的氧化应激的好方法。本综述的目的是介绍葡萄饮料和葡萄提取物对运动员氧化应激标志物的补充作用的最新进展。报告了多酚剂量、参与者特征和运动方案的数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74e5/7789302/175aac7f3d0b/12970_2020_395_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74e5/7789302/4d90d2824168/12970_2020_395_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74e5/7789302/175aac7f3d0b/12970_2020_395_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74e5/7789302/4d90d2824168/12970_2020_395_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74e5/7789302/175aac7f3d0b/12970_2020_395_Fig2_HTML.jpg

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