Vogel S B, Hocking M P, Woodward E R
Department of Surgery, University of Florida, College of Medicine, Gainesville 32610.
Am J Surg. 1988 Jan;155(1):57-62. doi: 10.1016/s0002-9610(88)80258-7.
From 1973 to 1986, 22 patients underwent Roux-Y gastrojejunostomy for the early postgastrectomy dumping syndrome. In the early years, five patients underwent Roux-Y conversion with the addition of a 10 cm antiperistaltic jejunal segment interposed between the Roux-Y limb and the stomach. Within 4 years, all five patients had the jejunal segment removed due to severe symptoms of gastric retention. These patients underwent reconstruction to create Roux-Y limb only and joined the pool of 17 patients who underwent Roux-Y diversion only for the dumping syndrome. Overall, 19 of 22 patients (86 percent) had almost complete resolution of their dumping symptoms on long-term follow-up. Three patients showed no improvement, two with severe gastric retention and one with recurrent dumping symptoms. Overall, 5 of 22 patients (23 percent) had moderate to severe early and late postoperative gastric retention necessitating medical treatment in three and subsequent near-total gastrectomy in two. Although other procedures such as pyloric reconstruction or the addition of isoperistaltic or antiperistaltic jejunal interpositions have been reported to be equally successful in delaying gastric emptying and resolving dumping symptoms, we have preferred Roux-Y diversion for the treatment of combined alkaline reflux gastritis and dumping or the pure early vasomotor postgastrectomy dumping syndrome. As reported, we have abandoned the use of an antiperistaltic jejunal segment interposed between the stomach and the Roux-Y limb due to the high rate of postoperative gastric retention.
1973年至1986年期间,22例患者因胃切除术后早期倾倒综合征接受了Roux-Y胃空肠吻合术。在最初几年,5例患者接受了Roux-Y改道术,即在Roux-Y肠袢与胃之间添加一段10 cm的逆蠕动空肠段。4年内,所有5例患者因严重的胃潴留症状而切除了空肠段。这些患者接受了重建手术,仅创建Roux-Y肠袢,并加入了17例仅因倾倒综合征接受Roux-Y转流术的患者群体。总体而言,22例患者中有19例(86%)在长期随访中倾倒症状几乎完全缓解。3例患者无改善,2例有严重胃潴留,1例有复发性倾倒症状。总体而言,22例患者中有5例(23%)有中度至重度的术后早期和晚期胃潴留,其中3例需要药物治疗,2例随后接受了近全胃切除术。尽管据报道,其他手术如幽门重建或添加顺蠕动或逆蠕动空肠间置术在延迟胃排空和缓解倾倒症状方面同样成功,但对于合并碱性反流性胃炎和倾倒或单纯早期血管舒缩性胃切除术后倾倒综合征的治疗,我们更倾向于采用Roux-Y转流术。如前所述,由于术后胃潴留发生率高,我们已放弃在胃与Roux-Y肠袢之间插入逆蠕动空肠段的做法。