Kozakiewicz Marcin
Department of Maxillofacial Surgery, Medical University of Lodz, 113th S. Żeromskiego, 90-549 Lodz, Poland.
Materials (Basel). 2021 Jan 6;14(2):237. doi: 10.3390/ma14020237.
Magnesium has been used as degradable fixation material for osteosynthesis, but it seems that mechanical strength is still a current issue in these fixations. The aim of this study was to evaluate the axial pull-out force of compression headless screws made of magnesium alloy during their resorption.
The tests included screws made for osteosynthesis of the mandible head: 2.2 mm diameter magnesium alloy MgYREZr (42 screws) and 2.5 mm diameter polylactic-co-glycolic acid (PLGA) (42 pieces, control). The screws were resorbed in Sørensen's buffer for 2, 4, 8, 12, and 16 weeks, and force was measured as the screw was pulled out from the polyurethane block.
The force needed to pull the screw out was significantly higher for MgYREZr screws than for PLGA ones ( < 0.01). Within eight weeks, the pull-out force for MgYREZr significantly decreased to one third of its initial value ( < 0.01). The dynamics of this decrease were greater than those of the pull-out force for PLGA screws ( < 0.05). After these eight weeks, the values for metal and polymer screws equalized. It seems that the described reduction of force requires taking into account when using magnesium screws. This will provide more stable resorbable metallic osteosynthesis.
镁已被用作可降解的骨固定材料,但在这些固定中机械强度似乎仍是当前的一个问题。本研究的目的是评估镁合金无头加压螺钉在吸收过程中的轴向拔出力。
测试包括用于下颌骨头骨固定的螺钉:直径2.2毫米的镁合金MgYREZr(42枚螺钉)和直径2.5毫米的聚乳酸-乙醇酸共聚物(PLGA)(42枚,对照)。将螺钉在索伦森缓冲液中吸收2、4、8、12和16周,当螺钉从聚氨酯块中拔出时测量力。
MgYREZr螺钉拔出所需的力显著高于PLGA螺钉(<0.01)。在八周内,MgYREZr螺钉的拔出力显著降至其初始值的三分之一(<0.01)。这种下降的动态变化大于PLGA螺钉拔出力的动态变化(<0.05)。八周后,金属螺钉和聚合物螺钉的值趋于相等。似乎在使用镁螺钉时需要考虑到所述的力的降低。这将提供更稳定的可吸收金属骨固定。