• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Pathological features of COVID-19-associated liver injury-a preliminary proteomics report based on clinical samples.

作者信息

Leng Ling, Cao Ruiyuan, Ma Jie, Lv Luye, Li Wei, Zhu Yunping, Wu Zhihong, Wang Manli, Zhou Yiwu, Zhong Wu

机构信息

Stem Cell and Regenerative Medicine Lab, Translational Medicine Center, Department of Medical Science Research Center, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100730, China.

National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China.

出版信息

Signal Transduct Target Ther. 2021 Jan 8;6(1):9. doi: 10.1038/s41392-020-00406-1.

DOI:10.1038/s41392-020-00406-1
PMID:33419962
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7791959/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17fc/7794307/f18bedd274ee/41392_2020_406_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17fc/7794307/f18bedd274ee/41392_2020_406_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17fc/7794307/f18bedd274ee/41392_2020_406_Fig1_HTML.jpg

相似文献

1
Pathological features of COVID-19-associated liver injury-a preliminary proteomics report based on clinical samples.新型冠状病毒肺炎相关肝损伤的病理特征——基于临床样本的初步蛋白质组学报告
Signal Transduct Target Ther. 2021 Jan 8;6(1):9. doi: 10.1038/s41392-020-00406-1.
2
Pathological features of COVID-19-associated lung injury: a preliminary proteomics report based on clinical samples.基于临床样本的 COVID-19 相关肺损伤的病理特征：初步蛋白质组学报告。
Signal Transduct Target Ther. 2020 Oct 15;5(1):240. doi: 10.1038/s41392-020-00355-9.
3
Deep spatial proteomics reveals region-specific features of severe COVID-19-related pulmonary injury.深度空间蛋白质组学揭示了与重症 COVID-19 相关的肺损伤的区域特异性特征。
Cell Rep. 2024 Feb 27;43(2):113689. doi: 10.1016/j.celrep.2024.113689. Epub 2024 Jan 18.
4
Characteristics and Mechanism of Liver Injury in 2019 Coronavirus Disease.2019冠状病毒病肝损伤的特征与机制
J Clin Transl Hepatol. 2020 Mar 28;8(1):13-17. doi: 10.14218/JCTH.2020.00019. Epub 2020 Mar 30.
5
Molecular consequences of SARS-CoV-2 liver tropism.SARS-CoV-2 肝脏嗜性的分子后果。
Nat Metab. 2022 Mar;4(3):310-319. doi: 10.1038/s42255-022-00552-6. Epub 2022 Mar 28.
6
Noninvasive proteomic biomarkers for alcohol-related liver disease.用于酒精性肝病的非侵入性蛋白质组学生物标志物。
Nat Med. 2022 Jun;28(6):1277-1287. doi: 10.1038/s41591-022-01850-y. Epub 2022 Jun 2.
7
Mechanism of Metabolic Response to Hepatectomy by Integrated Analysis of Gut Microbiota, Metabolomics, and Proteomics.通过肠道微生物组学、代谢组学和蛋白质组学的综合分析探讨肝切除术后代谢反应的机制。
Microbiol Spectr. 2023 Jun 15;11(3):e0206722. doi: 10.1128/spectrum.02067-22. Epub 2023 Apr 10.
8
Next-Generation Sequencing and Proteomics of Cerebrospinal Fluid From COVID-19 Patients With Neurological Manifestations.COVID-19 患者出现神经系统症状的脑脊液的下一代测序和蛋白质组学分析。
Front Immunol. 2021 Dec 9;12:782731. doi: 10.3389/fimmu.2021.782731. eCollection 2021.
9
[Preliminary study on differentially expressed proteins in a mouse model of secondary alveolar echinococcosis based on data independent acquisition proteomics].基于数据非依赖采集蛋白质组学的继发性肺泡型棘球蚴病小鼠模型差异表达蛋白质的初步研究
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2022 Feb 22;34(1):52-58. doi: 10.16250/j.32.1374.2021221.
10
Integrative proteomic profiling of lung tissues and blood in acute respiratory distress syndrome.急性呼吸窘迫综合征肺组织和血液的综合蛋白质组学分析。
Front Immunol. 2023 May 1;14:1158951. doi: 10.3389/fimmu.2023.1158951. eCollection 2023.

引用本文的文献

1
Mass Spectrometry Imaging: Revolutionizing Molecular Insights in Infectious Diseases Research.质谱成像：革新传染病研究中的分子洞察
Pathogens. 2025 Jun 30;14(7):645. doi: 10.3390/pathogens14070645.
2
Alterations of hepatic lipid content following COVID-19 in persons with type 2 diabetes.2型糖尿病患者感染新冠病毒后肝脏脂质含量的变化
BMJ Open Diabetes Res Care. 2025 Feb 18;13(1):e004727. doi: 10.1136/bmjdrc-2024-004727.
3
Aminoacyl-tRNA synthetase interactions in SARS-CoV-2 infection.SARS-CoV-2 感染中的氨酰-tRNA 合成酶相互作用。

本文引用的文献

1
Pathological features of COVID-19-associated lung injury: a preliminary proteomics report based on clinical samples.基于临床样本的 COVID-19 相关肺损伤的病理特征：初步蛋白质组学报告。
Signal Transduct Target Ther. 2020 Oct 15;5(1):240. doi: 10.1038/s41392-020-00355-9.
2
Clinical Features of Patients Infected With Coronavirus Disease 2019 With Elevated Liver Biochemistries: A Multicenter, Retrospective Study.新型冠状病毒病患者肝功能生化指标升高的临床特征：一项多中心回顾性研究。
Hepatology. 2021 Apr;73(4):1509-1520. doi: 10.1002/hep.31446. Epub 2020 Dec 22.
3
The MERS-CoV Receptor DPP4 as a Candidate Binding Target of the SARS-CoV-2 Spike.
Biochem Soc Trans. 2023 Dec 20;51(6):2127-2141. doi: 10.1042/BST20230527.
4
Diabetes Mellitus, Energy Metabolism, and COVID-19.糖尿病、能量代谢与 COVID-19
Endocr Rev. 2024 Mar 4;45(2):281-308. doi: 10.1210/endrev/bnad032.
5
COVID-19-related hyperglycemia is associated with infection of hepatocytes and stimulation of gluconeogenesis.COVID-19 相关的高血糖与肝细胞感染和糖异生刺激有关。
Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2217119120. doi: 10.1073/pnas.2217119120. Epub 2023 May 15.
6
Elucidation of the liver pathophysiology of COVID-19 patients using liver-on-a-chips.利用肝脏芯片阐明COVID-19患者的肝脏病理生理学。
PNAS Nexus. 2023 Mar 7;2(3):pgad029. doi: 10.1093/pnasnexus/pgad029. eCollection 2023 Mar.
7
Metabolomics Markers of COVID-19 Are Dependent on Collection Wave.新冠病毒病的代谢组学标志物取决于采集批次。
Metabolites. 2022 Jul 30;12(8):713. doi: 10.3390/metabo12080713.
8
Spatial region-resolved proteome map reveals mechanism of COVID-19-associated heart injury.空间区域分辨蛋白质组图谱揭示 COVID-19 相关心脏损伤的机制。
Cell Rep. 2022 Jun 14;39(11):110955. doi: 10.1016/j.celrep.2022.110955. Epub 2022 May 27.
9
The Landscape of Aminoacyl-tRNA Synthetases Involved in Severe Acute Respiratory Syndrome Coronavirus 2 Infection.参与严重急性呼吸综合征冠状病毒2感染的氨酰-tRNA合成酶概况
Front Physiol. 2022 Jan 26;12:818297. doi: 10.3389/fphys.2021.818297. eCollection 2021.
10
Establishment of Human Pluripotent Stem Cell-Derived Skin Organoids Enabled Pathophysiological Model of SARS-CoV-2 Infection.人多能干细胞衍生皮肤类器官的建立使 SARS-CoV-2 感染的病理生理学模型成为可能。
Adv Sci (Weinh). 2022 Mar;9(7):e2104192. doi: 10.1002/advs.202104192. Epub 2021 Dec 31.
中东呼吸综合征冠状病毒受体二肽基肽酶4作为严重急性呼吸综合征冠状病毒2刺突蛋白的候选结合靶点
iScience. 2020 Jun 26;23(6):101160. doi: 10.1016/j.isci.2020.101160. Epub 2020 May 13.
4
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.一种 SARS-CoV-2 蛋白相互作用图谱揭示了药物再利用的靶标。
Nature. 2020 Jul;583(7816):459-468. doi: 10.1038/s41586-020-2286-9. Epub 2020 Apr 30.