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南卡罗来纳州的一例感染病例:对已知地方病流行情况的一个潜在挑战。

A case of infection in South Carolina: A possible challenge to known endemicity.

作者信息

Summers Robert P, Abel William F, Sessions William S, Polley Eric M, Shirley Rhett M, Schnee Amanda E

机构信息

University of South Carolina School of Medicine Greenville, 607 Grove Rd., Greenville, SC 29605, United States.

Prisma Health System Department of Internal Medicine, 701 Grove Rd., Greenville, SC 29605, United States.

出版信息

IDCases. 2020 Dec 17;23:e01027. doi: 10.1016/j.idcr.2020.e01027. eCollection 2021.

DOI:10.1016/j.idcr.2020.e01027
PMID:33425680
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7776952/
Abstract

In the United States, is considered to be endemic to the Pacific Northwest and although uncommon, additional cases have been documented in other regions including the Southeastern United States. While it has been hypothesized in the past that may be endemic to the Southeastern United States, there remains a paucity of evidence. Here, we present a patient with no history of HIV/AIDS and no organ transplant and document the course of his disease and presentation. There were no adverse long-term neurological outcomes in this patient and the combination of steroid use, antifungal agents, and cerebrospinal fluid drainage resulted in his discharge from the hospital after 12 days. This patient's subacute presentation with vague neurological symptoms highlights the importance of understanding the treatment of rare causes of meningitis.

摘要

在美国,该病被认为在太平洋西北部地区为地方性疾病,尽管并不常见,但在包括美国东南部在内的其他地区也有更多病例被记录。过去曾有人推测该病可能在美国东南部为地方性疾病,但仍然缺乏证据。在此,我们介绍一名没有艾滋病毒/艾滋病病史且未接受过器官移植的患者,并记录其疾病过程和临床表现。该患者未出现不良的长期神经学后果,使用类固醇、抗真菌药物以及脑脊液引流相结合的治疗方法,使他在12天后出院。该患者以模糊的神经症状进行亚急性表现,突出了了解罕见脑膜炎病因治疗方法的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1df4/7776952/9ebdb21a198a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1df4/7776952/ac669af3ea0b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1df4/7776952/9ebdb21a198a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1df4/7776952/ac669af3ea0b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1df4/7776952/9ebdb21a198a/gr2.jpg

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The status of cryptococcosis in Latin America.拉丁美洲隐球菌病的现状。
Mem Inst Oswaldo Cruz. 2018;113(7):e170554. doi: 10.1590/0074-02760170554. Epub 2018 Apr 5.
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Species in the Complex Differ in Capsule and Cell Size following Growth under Capsule-Inducing Conditions.
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mSphere. 2016 Dec 28;1(6). doi: 10.1128/mSphere.00350-16. eCollection 2016 Nov-Dec.
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in an Immunocompetent Patient in the Southeastern United States.在美国东南部的一名免疫功能正常的患者中。
Case Rep Infect Dis. 2016;2016:8280915. doi: 10.1155/2016/8280915. Epub 2016 Nov 27.
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N Engl J Med. 2016 Jul 14;375(2):188. doi: 10.1056/NEJMc1605205.
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