Cho Jungheum, Ahn Hyungwoo, Hwang Sung Il, Lee Hak Jong, Choe Gheeyoung, Byun Seok-Soo, Hong Sung Kyu
Department of Radiology, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea.
Department of Pathology, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea.
Prostate Int. 2020 Dec;8(4):146-151. doi: 10.1016/j.prnil.2019.12.004. Epub 2020 Feb 26.
Biparametric (bp) magnetic resonance imaging (MRI) could be an alternative MRI for the detection of the clinically significant prostate cancer (csPCa).
To compare the accuracies of prostate cancer detection and localization between prebiopsy bpMRI and postbiopsy multiparametric MRI (mpMRI) taken on different days, using radical prostatectomy specimens as the reference standards.
Data of 41 total consecutive patients who underwent the following examinations and procedures between September 2015 and March 2017 were collected: (1) magnetic resonance- and/or ultrasonography-guided biopsy after bpMRI; (2) postbiopsy mpMRI; and (3) radical prostatectomy with csPCa. Two radiologists scored suspected lesions on bpMRI and mpMRI independently using Prostate Imaging Reporting and Data System version 2. The diagnostic accuracy of detecting csPCa and the Dice similarity coefficient were obtained. Apparent diffusion coefficient (ADC) ratios were also obtained for quantitative comparison between bpMRI and mpMRI.
Diagnostic accuracies on bpMRI and mpMRI were 0.83 and 0.82 for reader 1; 0.80 and 0.82 for reader 2. There are no significantly different values of diagnostic sensitivities or specificities between the readers or between MRI protocols. Intra-observer Dice similarity coefficient was significantly lower in reader 2, compared to that in reader 1 between the two MRI protocols. The range of mean ADC ratio was 0.281-0.635. There was no statistically significant difference in the ADC ratio between bpMRI and mpMRI.
Diagnostic performance of bpMRI without dynamic contrast enhancement MRI is not significantly different from mpMRI with dynamic contrast enhancement MRI in the detection of csPCa.
双参数（bp）磁共振成像（MRI）可能是检测临床显著前列腺癌（csPCa）的一种替代MRI方法。
以根治性前列腺切除术标本作为参考标准，比较活检前bpMRI和不同日期活检后多参数MRI（mpMRI）在前列腺癌检测和定位方面的准确性。
收集了2015年9月至2017年3月期间连续接受以下检查和程序的41例患者的数据：（1）bpMRI后磁共振和/或超声引导下活检；（2）活检后mpMRI；（3）csPCa根治性前列腺切除术。两名放射科医生使用前列腺影像报告和数据系统第2版独立对bpMRI和mpMRI上的可疑病变进行评分。获得检测csPCa的诊断准确性和Dice相似系数。还获得表观扩散系数（ADC）比值，用于bpMRI和mpMRI之间的定量比较。
读者1对bpMRI和mpMRI的诊断准确性分别为0.83和0.82；读者2为0.80和0.82。读者之间或MRI方案之间的诊断敏感性或特异性值无显著差异。在两种MRI方案之间，读者2的观察者内Dice相似系数显著低于读者1。平均ADC比值范围为0.281 - 0.635。bpMRI和mpMRI之间的ADC比值无统计学显著差异。
在检测csPCa方面，未进行动态对比增强MRI的bpMRI的诊断性能与进行动态对比增强MRI的mpMRI无显著差异。
