Department of Obstetrics and Gynecology Nursing, West China Second University Hospital, Sichuan University.
Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education.
Medicine (Baltimore). 2021 Jan 8;100(1):e24264. doi: 10.1097/MD.0000000000024264.
The physical and psychological condition of patients with gynaecological cancer has received much attention, but there is little research on spirituality in palliative care. This study aimed to investigate spiritual well-being and its association with quality of life, anxiety and depression in patients with gynaecological cancer. A cross-sectional study was conducted in China in 2019 with 705 patients diagnosed with primary gynaecological cancer. European Organisation for Research and Treatment of Cancer quality of life instruments (EORTC QLQ-SWB32 and EORTC QLQ-C30) and the Hospital Anxiety and Depression Scale were used to measure spiritual well-being, quality of life, anxiety and depression. Univariate and multiple linear regression analyses were performed to examine associations between spiritual well-being, quality of life, anxiety and depression. Functioning scales and global health status were positively correlated with spiritual well-being (P < .05). Anxiety and depression were negatively correlated with spiritual well-being (P < .05). Depression (-0.362, P < .001) was the strongest predictor of Existential score. Anxiety (-0.522, P < .001) was the only predictor of Relationship with self. Depression (-0.350, P < .001) and Global health (0.099, P = .011) were the strongest predictors of Relationship with others. Religion (-0.204, P < .001) and Depression (-0.196, P < .001) were the strongest predictors of Relationship with someone or something greater. Global health (0.337, P < .001) and Depression (-0.144, P < .001) were the strongest predictors of Global-SWB. Well spiritual well-being is associated with lower anxiety and depression, and better quality of life. Health providers should provide more spiritual care for non-religious patients and combine spiritual care with psychological counselling to help patients with gynaecological cancer, especially those who have low quality of life or severe symptoms, or experience anxiety or depression.
妇科癌症患者的身心状况备受关注，但姑息治疗中的灵性问题研究甚少。本研究旨在探讨妇科癌症患者的灵性幸福感及其与生活质量、焦虑和抑郁的关系。2019 年在中国进行了一项横断面研究，纳入了 705 例原发性妇科癌症患者。采用欧洲癌症研究与治疗组织生活质量问卷（EORTC QLQ-SWB32 和 EORTC QLQ-C30）和医院焦虑抑郁量表评估灵性幸福感、生活质量、焦虑和抑郁。采用单因素和多因素线性回归分析探讨灵性幸福感与生活质量、焦虑和抑郁的关系。功能量表和总体健康状况与灵性幸福感呈正相关（P<0.05）。焦虑和抑郁与灵性幸福感呈负相关（P<0.05）。抑郁（-0.362，P<0.001）是存在评分的最强预测因子。焦虑（-0.522，P<0.001）是自我关系的唯一预测因子。抑郁（-0.350，P<0.001）和总体健康（0.099，P=0.011）是与他人关系的最强预测因子。宗教（-0.204，P<0.001）和抑郁（-0.196，P<0.001）是与更伟大的某人或某事的关系的最强预测因子。总体健康（0.337，P<0.001）和抑郁（-0.144，P<0.001）是全球幸福感的最强预测因子。良好的灵性幸福感与较低的焦虑和抑郁以及更好的生活质量相关。卫生保健提供者应为非宗教患者提供更多的灵性关怀，并将灵性关怀与心理咨询相结合，以帮助妇科癌症患者，尤其是那些生活质量较低或症状严重，或有焦虑或抑郁的患者。
