Key Laboratory of Sensing Technology and Biomedical Instrument of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510006, PR China.
Shenzhen Lansi Institute of Artificial Intelligence in Medicine, Shenzhen, Guangdong, China.
Biomater Sci. 2021 Mar 10;9(5):1530-1546. doi: 10.1039/d0bm01747g.
Currently, the treatment and care of diabetic wounds, which generally possess the characteristics of a high amputation rate, high recurrence rate and high mortality, has developed into a worldwide challenge. Wound dressings have been playing an important role in diabetic wound treatment and continuously innovated to obtain many amazing properties. Among them, hydrogel dressings have become one of the most attractive and promising wound dressings because of their considerable moisture retention, biocompatibility and therapeutic properties. In recent years, with the in depth understanding of the pathogenesis of diabetic wounds, various functionalized hydrogel dressings have been reported and shown encouraging results, which has brought great benefits to the improvement of diabetic wounds. In this work, we will systematically and comprehensively summarize the advances of hydrogel dressings in diabetic wounds, aiming to provide not only theoretical support for hydrogel dressing devising but also inspiration for diabetic wound treatment.
目前，糖尿病伤口的治疗和护理已成为全球性挑战，这些伤口通常具有高截肢率、高复发率和高死亡率的特点。伤口敷料在糖尿病伤口治疗中发挥着重要作用，并不断创新以获得许多惊人的特性。其中，水凝胶敷料因其良好的保湿性、生物相容性和治疗性能而成为最具吸引力和前景的伤口敷料之一。近年来，随着对糖尿病伤口发病机制的深入了解，各种功能化水凝胶敷料相继被报道并取得了令人鼓舞的效果，这为改善糖尿病伤口带来了巨大的益处。在这项工作中，我们将系统全面地总结水凝胶敷料在糖尿病伤口中的研究进展，旨在不仅为水凝胶敷料的设计提供理论支持，也为糖尿病伤口治疗提供灵感。
