Department of Pulmonology, Respiratory Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Department of Infectious Diseases, Medical Specialties Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
BMC Pulm Med. 2021 Jan 12;21(1):24. doi: 10.1186/s12890-020-01379-1.
Pulmonary radiological findings of the novel coronavirus disease 2019 (COVID-19) have been well documented and range from scattered ground-glass infiltrates in milder cases to confluent ground-glass change, dense consolidation, and crazy paving in the critically ill. However, lung cavitation has not been commonly described in these patients. The objective of this study was to assess the incidence of pulmonary cavitation in patients with COVID-19 and describe its characteristics and evolution.
We conducted a retrospective review of all patients admitted to our institution with COVID-19 and reviewed electronic medical records and imaging to identify patients who developed pulmonary cavitation.
Twelve out of 689 (1.7%) patients admitted to our institution with COVID-19 developed pulmonary cavitation, comprising 3.3% (n = 12/359) of patients who developed COVID-19 pneumonia, and 11% (n = 12/110) of those admitted to the intensive care unit. We describe the imaging characteristics of the cavitation and present the clinical, pharmacological, laboratory, and microbiological parameters for these patients. In this cohort six patients have died, and six discharged home.
Cavitary lung disease in patients with severe COVID-19 disease is not uncommon, and is associated with a high level of morbidity and mortality.
新型冠状病毒病 2019（COVID-19）的肺部放射学表现已有详细记录，范围从轻度病例的散在磨玻璃影到重症患者的融合性磨玻璃影、致密实变和铺路石征。然而，这些患者中并未常描述肺空洞。本研究旨在评估 COVID-19 患者肺空洞的发生率，并描述其特征和演变。
我们对我院收治的所有 COVID-19 患者进行了回顾性分析，并查阅了电子病历和影像学资料，以确定发生肺空洞的患者。
我院收治的 689 例 COVID-19 患者中有 12 例（1.7%）发生肺空洞，其中 3.3%（n=12/359）的 COVID-19 肺炎患者和 11%（n=12/110）的重症监护病房患者发生肺空洞。我们描述了空洞的影像学特征，并介绍了这些患者的临床、药理学、实验室和微生物学参数。在该队列中，有 6 例患者死亡，6 例出院回家。
重症 COVID-19 患者的空洞性肺病并不少见，与高发病率和死亡率相关。
