Department of Public Health, Poznan University of Medical Sciences, Poznan, Poland.
Neurol Neurochir Pol. 2021;55(1):5-7. doi: 10.5603/PJNNS.a2021.0002. Epub 2021 Jan 13.
Zduńska et al. [1] present the results of a pilot study exploring changes in melatonin serum concentration in migraine patients, and the clinical implications of these changes.
Melatonin secretion may be altered for several reasons, and migraine is one of those clinical conditions where melatonin secretion can be changed. Correlations between migraine clinical phenotype and melatonin secretion pat-terns may bring exciting results.
Alterations in melatonin secretion in migraine has not been explained. Studies which aim at exploring the mechanism(s) of action of melatonin secretion in migraine patients may provide an insight into the pathogenesis of migraine and contribute to effective treatment options.
Zduńska 等人 [1] 报告了一项探索偏头痛患者血清褪黑素浓度变化及其临床意义的初步研究结果。
褪黑素的分泌可能会因多种原因而改变，偏头痛就是其中一种可能导致褪黑素分泌改变的临床情况。偏头痛临床表型与褪黑素分泌模式之间的相关性可能会带来令人兴奋的结果。
偏头痛患者褪黑素分泌的改变尚未得到解释。旨在探索偏头痛患者褪黑素分泌作用机制的研究，可能有助于深入了解偏头痛的发病机制，并为有效治疗方法提供依据。
