中国高血压发病率的长期趋势和地区差异：一项基于1991 - 2015年中国健康与营养调查的前瞻性队列研究
Long-term trends and regional variations of hypertension incidence in China: a prospective cohort study from the China Health and Nutrition Survey, 1991-2015.
作者信息
Luo Yunmei, Xia Fan, Yu Xuexin, Li Peiyi, Huang Wenzhi, Zhang Wei
机构信息
Institute of Hospital Management, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
West China Medical Publishers, West China Hospital, Sichuan University, Chngdu, Sichuan, China.
出版信息
BMJ Open. 2021 Jan 13;11(1):e042053. doi: 10.1136/bmjopen-2020-042053.
OBJECTIVE
The aim is to explore the trends of hypertension incidence and regional variations in China from 1991 to 2015.
DESIGN
A dynamic prospective cohort study.
SETTING
China Health and Nutrition Survey 1991-2015.
PARTICIPANTS
12 952 Chinese adults aged 18+ years.
PRIMARY OUTCOME MEASURES
Incident hypertension from 1993 to 2015.
RESULTS
Age-standardised hypertension incidence increased from 40.8 per 1000 person-years (95% CI 38.3 to 43.4) between 1993 and 1997 to 48.6 (95% CI 46.1 to 51.0) between 2011 and 2015. The increasing trends were further supported by results from subsequent extended Cox proportional hazard model. In addition, results from the modelling analysis showed that individuals in eastern, central and northeastern China had greater risks of hypertension occurrence in comparison with their counterparts in western China.
CONCLUSION
Hypertension incidence increased during the study period. The growth called for more attention on the health education and health promotion of individuals with great risks.
目的
探讨1991年至2015年中国高血压发病率的趋势及地区差异。
设计
动态前瞻性队列研究。
设置
1991 - 2015年中国健康与营养调查。
参与者
12952名18岁及以上的中国成年人。
主要观察指标
1993年至2015年的高血压发病情况。
结果
年龄标准化高血压发病率从1993年至1997年的每1000人年40.8（95%CI 38.3至43.4）增加到2011年至2015年的48.6（95%CI 46.1至51.0）。后续扩展的Cox比例风险模型结果进一步支持了这一上升趋势。此外，模型分析结果表明，与中国西部的同龄人相比，中国东部、中部和东北部的个体患高血压的风险更高。
结论
在研究期间高血压发病率有所上升。这种增长需要更多地关注高危个体的健康教育和健康促进。
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