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Anti-ageing effects of protein restriction unpacked.

作者信息

Hill Cristal M, Kaeberlein Matt

出版信息

Nature. 2021 Jan;589(7842):357-358. doi: 10.1038/d41586-020-03662-x.

DOI:10.1038/d41586-020-03662-x
PMID:33446907
Abstract
摘要

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Anti-ageing effects of protein restriction unpacked.蛋白质限制的抗衰老作用解析
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2
New Horizons: Dietary protein, ageing and the Okinawan ratio.新视野:膳食蛋白质、衰老与冲绳比例
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3
Protein restriction during fetal and neonatal development in the rat alters reproductive function and accelerates reproductive ageing in female progeny.大鼠在胎儿期和新生儿期发育过程中蛋白质限制会改变生殖功能,并加速雌性后代的生殖衰老。
J Physiol. 2006 Apr 1;572(Pt 1):97-108. doi: 10.1113/jphysiol.2005.103903. Epub 2006 Feb 23.
4
Spermidine supplementation and protein restriction protect from organismal and brain aging independently.补充亚精胺和限制蛋白质摄入可分别独立地预防机体和大脑衰老。
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Dietary protein, aging and nutritional geometry.饮食蛋白质、衰老与营养几何
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The anti-ageing action of dietary restriction.
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The conserved role of protein restriction in aging and disease.蛋白质限制在衰老和疾病中的保守作用。
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Methionine restriction and life-span control.蛋氨酸限制与寿命控制。
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The disparity of platelet factor 4 and platelets in individuals of different ages.不同年龄段个体中血小板第4因子和血小板的差异。
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Once-daily feeding is associated with better health in companion dogs: results from the Dog Aging Project.一日一次的喂养与伴侣犬的健康状况改善有关:来自犬类衰老研究项目的结果。
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Are fat and sugar just as detrimental in old age?

本文引用的文献

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Lifelong restriction of dietary branched-chain amino acids has sex-specific benefits for frailty and lifespan in mice.终身限制饮食中支链氨基酸可特异性改善雌雄小鼠的虚弱和寿命。
Nat Aging. 2021 Jan;1(1):73-86. doi: 10.1038/s43587-020-00006-2. Epub 2021 Jan 14.
2
Branched chain amino acids, aging and age-related health.支链氨基酸、衰老与衰老相关健康。
Ageing Res Rev. 2020 Dec;64:101198. doi: 10.1016/j.arr.2020.101198. Epub 2020 Oct 24.
3
Effect of rapamycin on aging and age-related diseases-past and future.雷帕霉素对衰老及与年龄相关疾病的影响——过去与未来
脂肪和糖在老年时同样有害吗?
Geroscience. 2021 Aug;43(4):1615-1625. doi: 10.1007/s11357-021-00390-6. Epub 2021 Jun 8.
Geroscience. 2021 Jun;43(3):1135-1158. doi: 10.1007/s11357-020-00274-1. Epub 2020 Oct 10.
4
Genetic and metabolomic architecture of variation in diet restriction-mediated lifespan extension in Drosophila.饮食限制介导的果蝇寿命延长的遗传和代谢组学结构。
PLoS Genet. 2020 Jul 9;16(7):e1008835. doi: 10.1371/journal.pgen.1008835. eCollection 2020 Jul.
5
Effect of diet protein restriction on progression of chronic kidney disease: A systematic review and meta-analysis.饮食蛋白限制对慢性肾脏病进展的影响:系统评价和荟萃分析。
PLoS One. 2018 Nov 7;13(11):e0206134. doi: 10.1371/journal.pone.0206134. eCollection 2018.
6
Homeostatic sensing of dietary protein restriction: A case for FGF21.膳食蛋白质限制的内稳态感知:以 FGF21 为例。
Front Neuroendocrinol. 2018 Oct;51:125-131. doi: 10.1016/j.yfrne.2018.06.002. Epub 2018 Jun 8.
7
Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice.生酮饮食可降低中年死亡率并改善衰老小鼠的记忆。
Cell Metab. 2017 Sep 5;26(3):547-557.e8. doi: 10.1016/j.cmet.2017.08.004.
8
A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.生酮饮食可延长成年小鼠的寿命和健康跨度。
Cell Metab. 2017 Sep 5;26(3):539-546.e5. doi: 10.1016/j.cmet.2017.08.005.
9
Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health.减少支链氨基酸的摄入量可改善代谢健康。
Cell Rep. 2016 Jul 12;16(2):520-530. doi: 10.1016/j.celrep.2016.05.092. Epub 2016 Jun 23.
10
The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.硒蛋白与GATOR2相互作用,以负向调节mTORC1上游的氨基酸感应通路。
Cell Rep. 2014 Oct 9;9(1):1-8. doi: 10.1016/j.celrep.2014.09.014. Epub 2014 Sep 25.