Allen M L, Orr W C, Woodruff D M, Robinson M G
HCA Presbyterian Hospital, Oklahoma City, Oklahoma.
Am J Gastroenterol. 1988 Mar;83(3):287-90.
The present study documents the accuracy of a commercially available ambulatory esophageal pH instrument. The distal esophagus of five subjects with daily heartburn was monitored for 24 h in the laboratory via an antimony pH electrode. The computer output from the ambulatory unit was compared to the on-line recording in terms of all events in which the pH dropped below four. A signal detection model was used, with an on-line pH tracing serving as the criterion response. The events noted as true positives (80%) were an accurate representation by the computer output of the events of pH less than four displayed by the on-line recording. The processing done by this particular ambulatory system tends to actually "ignore" transient pH drops (18% false negatives) and, may, in fact, provide more physiologically meaningful information than hardwired analog techniques for 24-h pH monitoring. The results confirm that ambulatory pH monitoring can produce meaningful and reliable physiological data concerning gastroesophageal reflux.
本研究记录了一种市售动态食管pH监测仪的准确性。在实验室中，通过锑pH电极对5名每日有烧心症状的受试者的食管远端进行了24小时监测。将动态监测仪的计算机输出结果与在线记录中pH值低于4的所有事件进行了比较。使用了信号检测模型，将在线pH追踪作为标准反应。被记为真阳性的事件（80%）由计算机输出准确呈现了在线记录中显示的pH值低于4的事件。该特定动态监测系统所进行的处理往往会实际“忽略”短暂的pH值下降（18%的假阴性），并且实际上可能比硬连线模拟技术提供更具生理意义的24小时pH监测信息。结果证实，动态pH监测能够产生有关胃食管反流的有意义且可靠的生理数据。
