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超级传播者:社区中的潜伏危险。

Superspreaders: A Lurking Danger in the Community.

机构信息

Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Lady Hardinge Medical College New Delhi, Delhi, India.

出版信息

J Prim Care Community Health. 2021 Jan-Dec;12:2150132720987432. doi: 10.1177/2150132720987432.

DOI:10.1177/2150132720987432
PMID:33448254
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7812391/
Abstract

A "superspreader" refers to an unusually contagious organism infected with a disease. With respect to a human borne illnesses, a superspreader is someone who is more likely to infect other humans when compared to a typically infected person. The existence of human superspreaders is deeply entrenched in history; the most famous case being that of Typhoid Mary. Through contact tracing, epidemiologists have identified human superspreaders in measles, tuberculosis, rubella, monkeypox, smallpox, Ebola hemorrhagic fever, and SARS. The recent outbreak of Coronavirus disease (COVID-19) has shifted the focus back on the superspreaders. We herein present a case report of a COVID-19 superspreader with a hitherto unusually high number of infected contacts. The index case was a 33 year old male who resided in a low income settlement comprising of rehabilitated slum dwellers and worked as a healthcare worker (HCW) in a tertiary care hospital and had tested positive for COVID-19.On contact tracing, he had a total of 125 contacts, of which 49 COVID-19 infections had direct or indirect contact with the index case, qualifying him as a "superspreader." This propagated infection led to an outbreak in the community. Contact tracing, testing and isolation of such superspreaders from the other members of the community is essential to stop the spread of this disease and contain the COVID-19 pandemic.

摘要

“超级传播者”指的是一种具有异常传染性的生物体,感染了某种疾病。就人类携带的疾病而言,超级传播者是指与一般感染者相比,更有可能感染其他人类的人。人类超级传播者的存在在历史上根深蒂固;最著名的例子是伤寒玛丽。通过接触者追踪,流行病学家在麻疹、结核病、风疹、猴痘、天花、埃博拉出血热和 SARS 中已经确定了人类超级传播者。最近冠状病毒病(COVID-19)的爆发再次将焦点转移到超级传播者身上。在此,我们报告了一例 COVID-19 超级传播者的病例,该病例的感染接触者数量异常之多。该指数病例是一名 33 岁男性,居住在一个低收入的贫民窟改造定居点,在一家三级保健医院工作,是一名医疗保健工作者(HCW),COVID-19 检测呈阳性。在接触者追踪中,他共有 125 个接触者,其中 49 例 COVID-19 感染与该指数病例有直接或间接接触,使他成为一名“超级传播者”。这种传播感染导致了社区内的爆发。对这些超级传播者进行接触者追踪、检测和隔离,对于阻止疾病传播和控制 COVID-19 大流行至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6ca/7812391/6dbc8e38984a/10.1177_2150132720987432-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6ca/7812391/6dbc8e38984a/10.1177_2150132720987432-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6ca/7812391/6dbc8e38984a/10.1177_2150132720987432-fig1.jpg

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