Ocal F Ceyda Akin, Karacayli Ceren, Coban Volkan Kenan, Satar Bulent
Department of Otorhinolaryngology, University of Health Sciences, Gulhane Traning and Research Hospital, Ankara, Turkey.
Department of Audiology, University of Health Sciences, Ankara, Turkey.
J Audiol Otol. 2021 Apr;25(2):98-103. doi: 10.7874/jao.2020.00486. Epub 2021 Jan 19.
The aim of the study was to compare effects of tone-burst (TB) and narrow-band (NB) Claus Elberling (CE)-chirp stimuli on amplitude, latency and interaural asymmetry ratio (IAR) of cervical vestibular evoked myogenic potentials (cVEMP) in healthy individuals.
The study included 50 healthy volunteers. cVEMP procedure was carried out using 500 Hz TB and NB-CE-chirp stimulus (360-720 Hz, up-chirp) in random order. cVEMP were recorded at 100 dB nHL. For each ear and each stimulus, P1 latency, N1 latency and P1N1 amplitude were measured. IAR was also calculated.
Mean age was 26.66±9.48 years. cVEMP's in response to both TB and NB CE-chirp stimuli were obtained in all subjects. No statistically significant difference in P1 latency, N1 latency, and P1N1 amplitude was found between the right and left ears for both TB and NB CE-chirp stimuli (p>0.05). In both sides, P1 and N1 latencies were significantly shorter in NB CE-chirp stimulation compared to TB stimulation (p=0.000). In both sides, no statistically significant difference was found in P1N1 amplitude between two types of stimuli (p>0.05).
The chirp stimulus produces robust but earlier cVEMP than TB does. This largest series study on NB chirp cVEMP shows that NB chirp is a good and new reliable alternative.
本研究旨在比较短纯音（TB）和窄带（NB）克劳斯·埃尔伯林（CE）-啁啾刺激对健康个体颈前庭诱发肌源性电位（cVEMP）的幅度、潜伏期和双耳不对称率（IAR）的影响。
本研究纳入50名健康志愿者。采用500 Hz短纯音和NB-CE-啁啾刺激（360 - 720 Hz，上升啁啾）以随机顺序进行cVEMP检查。cVEMP在100 dB nHL下记录。对每只耳朵和每种刺激，测量P1潜伏期、N1潜伏期和P1N1幅度。同时计算IAR。
平均年龄为26.66±9.48岁。所有受试者均获得了对TB和NB CE-啁啾刺激的cVEMP。对于TB和NB CE-啁啾刺激，左右耳在P1潜伏期、N1潜伏期和P1N1幅度方面均未发现统计学显著差异（p>0.05）。在两侧，与TB刺激相比，NB CE-啁啾刺激下P1和N1潜伏期显著更短（p = 0.000）。在两侧，两种刺激类型在P1N1幅度方面未发现统计学显著差异（p>0.05）。
啁啾刺激产生的cVEMP比短纯音更稳定但潜伏期更早。这项关于NB啁啾cVEMP的最大系列研究表明，NB啁啾是一种良好且可靠的新选择。
