Çoban Volkan Kenan, Akın Öçal Fatma Ceyda, Karaçaylı Ceren, Satar Bülent
Department of Otorhinolaryngology, University of Health Science Turkey, Gülhane Traning and Research Hospital, Ankara, Turkey.
Department of Audiology, University of Health Science Turkey, Gülhane Faculty of Health Science, Ankara, Turkey.
Auris Nasus Larynx. 2021 Aug;48(4):590-593. doi: 10.1016/j.anl.2020.11.008. Epub 2020 Dec 7.
This study aims to investigate the differences of N1 latency, P1 latency and N1P1 amplitude in response to bone conducted 500 Hz tone burst and narrowband CE chirp stimulus in ocular vestibular evoked myogenic potentials (oVEMPs).
Forty-two healthy volunteers were included in this prospective study. Subjects with abnormal otological examinations and otological diseases were excluded. oVEMPs were randomly recorded in response to BC 500 Hz narrowband (NB) chirp stimulus and BC 500 Hz tone burst. The stimulus intensity was 50 dB nHL for both 500 Hz tone burst and 500 Hz NB CE chirp stimulus. P1 latency, N1 latency, and N1P1 amplitude were measured, and these measurements were compared between these two types of stimuli.
Both types of stimuli elicited oVEMP in all subjects. N1 latency and P1 latency were significantly shorter (6.41 ms vs 10.84 ms; 10.64 ms vs 15.56 ms, respectively) for chirp stimulus (p < 0.05). N1P1 amplitude was significantly higher (11.64 vs 7.18 μV) for NB chirp stimulus (p < 0.05).
It is reasonable to conclude that the NB CE chirp stimulus is effective to elicit robust BC oVEMP in healthy subjects.
本研究旨在探讨在眼性前庭诱发肌源性电位（oVEMPs）中，对骨传导500Hz短纯音和窄带CE啁啾刺激的反应，N1潜伏期、P1潜伏期和N1P1波幅的差异。
42名健康志愿者纳入本前瞻性研究。排除耳科检查异常和患有耳科疾病的受试者。随机记录oVEMPs对骨传导500Hz窄带（NB）啁啾刺激和骨传导500Hz短纯音的反应。500Hz短纯音和500Hz NB CE啁啾刺激的刺激强度均为50dB nHL。测量P1潜伏期、N1潜伏期和N1P1波幅，并比较这两种刺激之间的测量结果。
两种刺激在所有受试者中均诱发了oVEMP。啁啾刺激的N1潜伏期和P1潜伏期显著更短（分别为6.41ms对10.84ms；10.64ms对15.56ms）（p<0.05）。NB啁啾刺激的N1P1波幅显著更高（11.64对7.18μV）（p<0.05）。
可以合理地得出结论，NB CE啁啾刺激能有效地在健康受试者中诱发强烈的骨传导oVEMP。
