C T Sulaiman, M Deepak, P R Ramesh, K Mahesh, E M Anandan, Balachandran Indira
Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, Malappuram, Kerala 676503 India.
Clinical Research Department, Arya Vaidya Sala, Kottakkal, Kerala India.
Beni Suef Univ J Basic Appl Sci. 2021;10(1):2. doi: 10.1186/s43088-020-00089-1. Epub 2021 Jan 11.
The novel coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is the global health concern since December 2019. It has become a big challenge for the researchers to find a solution for this newly evolved pandemic. In Ayurveda point of view, COVID-19 is a (epidemic disease), a situation where the environment-air, water, land, and seasons-is vitiated, causing a simultaneous manifestation of a disease among large populations. The aim of this study is to identify the active compounds of selected Ayurveda medicines recommended for COVID-19.
The selected preparations are traditionally recommended for the management of various kinds of fever including the infectious ones and to enhance the immunity. HPTLC analysis of the same showed presence of many active molecules like umbelliferone, scopoletin, caffeic acid, ferulic acid, gallic acid, piperine, curcumin, berberine, and palmatine.
The study provided valuable scientific data regarding the active ingredients of the selected medicines with proven therapeutic potentials like anti-viral, immunomodulatory, and anti-inflammatory activities.
2019年新型冠状病毒病（COVID-19）由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起，自2019年12月以来一直是全球关注的健康问题。对于研究人员来说，找到解决这种新出现的大流行病的方法已成为一项巨大挑战。从阿育吠陀的角度来看，COVID-19是一种（流行病），即环境——空气、水、土地和季节——受到污染，导致大量人群同时出现疾病的情况。本研究的目的是确定推荐用于COVID-19的选定阿育吠陀药物的活性成分。
所选制剂传统上推荐用于治疗包括感染性发热在内的各种发热，并增强免疫力。对其进行的高效薄层色谱分析表明存在许多活性分子，如伞形花内酯、东莨菪素、咖啡酸、阿魏酸、没食子酸、胡椒碱、姜黄素、小檗碱和巴马汀。
该研究提供了有关所选药物活性成分的宝贵科学数据，这些成分具有抗病毒、免疫调节和抗炎等已证实的治疗潜力。
