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关于放射治疗计划系统中骨剂量到水剂量的转换

On the conversion of dose to bone to dose to water in radiotherapy treatment planning systems.

作者信息

Reynaert Nick, Crop Frederik, Sterpin Edmond, Kawrakow Iwan, Palmans Hugo

机构信息

Institut Jules Bordet, Belgium.

Centre Oscar Lambret, Lille, France.

出版信息

Phys Imaging Radiat Oncol. 2018 Feb 9;5:26-30. doi: 10.1016/j.phro.2018.01.004. eCollection 2018 Jan.

DOI:10.1016/j.phro.2018.01.004
PMID:33458365
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7807555/
Abstract

BACKGROUND AND PURPOSE

Conversion factors between dose to medium (D) and dose to water (D) provided by treatment planning systems that model the patient as water with variable electron density are currently based on stopping power ratios. In the current paper it will be illustrated that this conversion method is not correct.

MATERIALS AND METHODS

Monte Carlo calculations were performed in a phantom consisting of a 2 cm bone layer surrounded by water. D was obtained by modelling the bone layer as water with the electron density of bone. Conversion factors between D and D were obtained and compared to stopping power ratios and ratios of mass-energy absorption coefficients in regions of electronic equilibrium and interfaces. Calculations were performed for 6 MV and 20 MV photon beams.

RESULTS

In the region of electronic equilibrium the stopping power ratio of water to bone (1.11) largely overestimates the conversion obtained using the Monte Carlo calculations (1.06). In that region the MC dose conversion corresponds to the ratio of mass energy absorption coefficients. Near the water to bone interface, the MC ratio cannot be determined from stopping powers or mass energy absorption coefficients.

CONCLUSION

Stopping power ratios cannot be used for conversion from D to D provided by treatment planning systems that model the patient as water with variable electron density, either in regions of electronic equilibrium or near interfaces. In regions of electronic equilibrium mass energy absorption coefficient ratios should be used. Conversions at interfaces require detailed MC calculations.

摘要

背景与目的

将患者模拟为具有可变电子密度的水的治疗计划系统所提供的介质剂量(D)与水剂量(D)之间的转换因子目前基于阻止本领比。在本文中将说明这种转换方法是不正确的。

材料与方法

在一个由2厘米厚的骨层被水包围的体模中进行蒙特卡罗计算。通过将骨层模拟为具有骨电子密度的水来获得D。获得D与D之间的转换因子,并与电子平衡区域和界面处的阻止本领比以及质能吸收系数比进行比较。对6兆伏和20兆伏光子束进行计算。

结果

在电子平衡区域,水与骨的阻止本领比(1.11)大大高估了使用蒙特卡罗计算得到的转换因子(1.06)。在该区域,蒙特卡罗剂量转换对应于质能吸收系数比。在水与骨界面附近,蒙特卡罗比不能从阻止本领或质能吸收系数中确定。

结论

阻止本领比不能用于将模拟患者为具有可变电子密度的水的治疗计划系统所提供的D转换为D,无论是在电子平衡区域还是在界面附近。在电子平衡区域应使用质能吸收系数比。界面处的转换需要详细的蒙特卡罗计算。

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