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高能电子束的现场剂量学审计。

An on-site dosimetry audit for high-energy electron beams.

作者信息

de Prez Leon, Heukelom Stan, Jansen Bartel, Jansen Wim, van de Kamer Jeroen, van Klink Wenze, Kok Elfried, Perik Thijs, de Pooter Jacco, Wittkämper Frits

机构信息

VSL - Dutch Metrology Institute, Delft, The Netherlands.

VU University Medical Center, Amsterdam, The Netherlands.

出版信息

Phys Imaging Radiat Oncol. 2018 Feb 27;5:44-51. doi: 10.1016/j.phro.2018.02.001. eCollection 2018 Jan.

Abstract

BACKGROUND AND PURPOSE

External dosimetry audits are powerful quality assurance instruments for radiotherapy. The aim of this study was to implement an electron dosimetry audit based on a contemporary code of practice within the requirements for calibration laboratories performing proficiency tests. This involved the determination of suitable acceptance criteria based on thorough uncertainty analyses.

MATERIALS AND METHODS

Subject of the audit was the determination of absorbed dose to water, , and the beam quality specifier, . Fifteen electron beams were measured in four institutes according to the Belgian-Dutch code of practice for high-energy electron beams. The expanded uncertainty ( = 2) for the values was 3.6% for a Roos chamber calibrated in Co and 3.2% for a Roos chamber cross-calibrated against a Farmer chamber. The expanded uncertainty for the beam quality specifier, , was 0.14 cm. The audit acceptance levels were based on the expanded uncertainties for the comparison results and estimated to be 2.4%.

RESULTS

The audit was implemented and validated successfully. All audit results were satisfactory with differences in values mostly smaller than 0.5% and always smaller than 1%. Except for one, differences in were smaller than 0.2 cm and always smaller than 0.3 cm.

CONCLUSIONS

An electron dosimetry audit based on absorbed dose to water and present-day requirements for calibration laboratories performing proficiency tests was successfully implemented. It proved international traceability of the participants value with an uncertainty better than 3.6% ( = 2).

摘要

背景与目的

外照射剂量学审核是放射治疗强有力的质量保证手段。本研究的目的是依据当代操作规范,在校准实验室进行能力验证测试的要求范围内开展电子剂量学审核。这涉及基于全面的不确定度分析确定合适的验收标准。

材料与方法

审核的对象是水吸收剂量(D_{w})以及射束质指标(R_{50})的测定。按照比利时 - 荷兰高能电子束操作规范,在四个机构中对15条电子束进行了测量。对于在钴源中校准的Roos电离室,(D_{w})值的扩展不确定度((k = 2))为3.6%,对于与Farmer电离室交叉校准的Roos电离室,扩展不确定度为3.2%。射束质指标(R_{50})的扩展不确定度为0.14厘米。审核验收水平基于比较结果的扩展不确定度,估计为2.4%。

结果

审核得以成功实施并验证。所有(D_{w})审核结果均令人满意,(D_{w})值的差异大多小于0.5%,且始终小于1%。除一个结果外,(R_{50})的差异小于0.2厘米,且始终小于0.3厘米。

结论

基于水吸收剂量并符合校准实验室进行能力验证测试的当前要求的电子剂量学审核得以成功实施。结果证明参与者测量值具有国际可溯源性,不确定度优于3.6%((k = 2))。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c9/7807662/89c2d9f4a48d/gr1.jpg

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