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土耳其风湿病联盟在当前文献及2018年欧洲抗风湿病联盟建议指导下对手部骨关节炎管理的建议

The Turkish League Against Rheumatism Recommendations for the Management of Hand Osteoarthritis Under Guidance of the Current Literature and 2018 European League Against Rheumatism Recommendations.

作者信息

Ayhan Fikriye Figen, Sunar İsmihan, Umay Ebru, Keskİn Dilek, Altan Lale, DİnÇer Fitnat, DuruÖz Tuncay, Karalezlİ Nazım, Kuran Banu, Tuncer Tiraje

机构信息

Department of Physical Medicine and Rehabilitation, Uşak University, School of Medicine, Uşak, Turkey.

Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Ankara University, School of Medicine, Ankara, Turkey.

出版信息

Arch Rheumatol. 2020 Jan 8;35(3):309-320. doi: 10.46497/ArchRheumatol.2020.7693. eCollection 2020 Sep.

Abstract

OBJECTIVES

This study aims to explore the accordance to the 2018 European League Against Rheumatism (EULAR) recommendations for the management of hand osteoarthritis (OA) among the Turkish League Against Rheumatism (TLAR) expert panel and composition of TLAR recommendations for the management of hand OA under guidance of the current literature.

MATERIALS AND METHODS

The TLAR convener designated an expert panel of 10 physicians experienced in hand OA for this process. The 2018 EULAR recommendations for the management of hand OA and the systematic review of the literature were sent to the expert panel via e-mails. The e-mail process which included Delphi round surveys was completed. The EULAR standard operational procedure Appraisal of Guidelines for Research and Evaluation II was followed. The level of agreement was calculated for each item and presented as mean, standard deviations, minimum and maximum and comparisons of 2018 EULAR recommendations were performed.

RESULTS

Five overarching principles and 10 recommendations were discussed. Revisions were held for the sixth, seventh, and ninth recommendations with lowest level of agreements. These recommendations were revised in accordance with suggestions from the experts and re-voted. The revised forms were approved despite the lack of statistically significant difference between these forms (p=0.400, p=0.451, p=0.496, respectively). Except for the ninth recommendation about surgery (p=0.008), no significant difference in level of agreements was observed between the EULAR and TLAR hand OA recommendations. The 11th recommendation about paraffin bath was added.

CONCLUSION

The optimal treatment of hand OA consists of personalized non-pharmacological (self-management, exercise, splint), pharmacological (topical non-steroidal anti-inflammatory drugs as the first choice), and interventional procedures (only for refractory cases) based on shared decision between the patient and physician. TLAR hand OA recommendations were created mainly based on the most recent literature and the last EULAR hand OA management recommendations, which are widely approved among the TLAR experts.

摘要

目的

本研究旨在探讨土耳其风湿病联盟(TLAR)专家小组对2018年欧洲抗风湿病联盟(EULAR)手部骨关节炎(OA)管理建议的遵循情况,以及在当前文献指导下TLAR手部OA管理建议的构成。

材料与方法

TLAR召集人为此指定了一个由10名手部OA经验丰富的医生组成的专家小组。通过电子邮件将2018年EULAR手部OA管理建议和文献系统综述发送给专家小组。包括德尔菲轮次调查的电子邮件流程完成。遵循EULAR研究与评估指南评估II的标准操作程序。计算每个项目的一致性水平,并以均值、标准差、最小值和最大值表示,同时对2018年EULAR建议进行比较。

结果

讨论了五项总体原则和十条建议。对一致性水平最低的第六、第七和第九条建议进行了修订。根据专家建议对这些建议进行修订并重新投票。尽管这些修订后的表格之间没有统计学上的显著差异(分别为p = 0.400、p = 0.451、p = 0.496),但仍获得批准。除了关于手术的第九条建议(p = 0.008)外,EULAR和TLAR手部OA建议之间在一致性水平上没有显著差异。增加了关于石蜡浴的第十一条建议。

结论

手部OA的最佳治疗包括基于患者和医生共同决策的个性化非药物治疗(自我管理、运动、夹板)、药物治疗(首选外用非甾体抗炎药)和介入治疗(仅用于难治性病例)。TLAR手部OA建议主要基于最新文献和最新的EULAR手部OA管理建议制定,在TLAR专家中得到广泛认可。

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