Smojver Igor, Vuletić Marko, Gerbl Dražena, Budimir Ana, Sušić Mato, Gabrić Dragana
DDM, Private Hospital St. Catherine, 10 000 Zagreb, Croatia.
DDM, Department of Oral Surgery, School of Dental Medicine, University of Zagreb, 10 000 Zagreb, Croatia.
Materials (Basel). 2021 Jan 14;14(2):385. doi: 10.3390/ma14020385.
The microenvironment of the oral cavity is altered when an implant, a biocompatible foreign body, is inserted into the mouth. Bacteria settle in the tissues in and around the implant due to the passage of microorganisms through the microgap at the connection of the implant and prosthetic abutment. To prevent colonization of the implant by microorganisms, one idea is to use sealing and antimicrobial materials to decontaminate the implant-abutment interface and close the microgap. The purpose of this study is to evaluate the antimicrobial efficacy and permeability of different types of sealing materials at the implant-abutment interface, under static conditions. Three different sealing material (GapSeal gel, Oxysafe gel and Flow.sil) were used for sealing the implant-abutment interfaces in 60 titanium dental implants, which were first contaminated with a solution containing and for 14 days under an aerobic condition. Results showed that a complete seal against bacterial infection was not formed at the implant-abutment interface, while for fungal infections, only GapSeal material helped to prevent microleakage. Findings of this in vitro study reported that application of sealing material before abutment connection may reduce peri-implant bacterial and fungal population compared with the interface without sealing material.
当将作为生物相容性异物的种植体植入口腔时，口腔的微环境会发生改变。由于微生物通过种植体与修复基台连接处的微间隙，细菌会在种植体及其周围的组织中定植。为防止微生物在种植体上定植，一种想法是使用密封和抗菌材料对种植体-基台界面进行去污并封闭微间隙。本研究的目的是在静态条件下评估不同类型密封材料在种植体-基台界面的抗菌效果和渗透性。三种不同的密封材料（GapSeal凝胶、Oxysafe凝胶和Flow.sil）用于密封60颗钛牙种植体的种植体-基台界面，这些种植体首先在有氧条件下用含有 和 的溶液污染14天。结果表明，在种植体-基台界面未形成完全防止细菌感染的密封，而对于真菌感染，只有GapSeal材料有助于防止微渗漏。这项体外研究的结果报告称，与未使用密封材料的界面相比，在连接基台之前应用密封材料可能会减少种植体周围的细菌和真菌数量。
