• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

仰光大学医学 1 分校解剖课期间的室内甲醛浓度、个人甲醛暴露与临床症状

Indoor Formaldehyde Concentration, Personal Formaldehyde Exposure and Clinical Symptoms during Anatomy Dissection Sessions, University of Medicine 1, Yangon.

机构信息

Department of Physiology, University of Medicine 1, Yangon 11014, Myanmar.

Faculty and Graduate School of Engineering, Chiba University, Chiba 263-8522, Japan.

出版信息

Int J Environ Res Public Health. 2021 Jan 15;18(2):712. doi: 10.3390/ijerph18020712.

DOI:10.3390/ijerph18020712
PMID:33467564
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7830549/
Abstract

The formaldehyde (FA) embalming method, the world's most common protocol for the fixation of cadavers, has been consistently used in medical universities in Myanmar. This study was designed to examine the indoor FA concentrations in anatomy dissection rooms, an exposed site, and lecture theater, an unexposed control site, and to access personal exposure levels of FA and clinical symptoms of medical students and instructors. In total, 208 second year medical students (1/2019 batch) and 18 instructors from Department of Anatomy, University of Medicine 1, participated. Thirteen dissection sessions were investigated from February 2019 to January 2020. Diffusive sampling devices were used as air samplers and high-performance liquid chromatography was used for measurement of FA. Average indoor FA concentration of four dissection rooms was 0.43 (0.09-1.22) ppm and all dissection rooms showed indoor concentrations above the occupational exposure limits and short-term exposure limit for general population. Personal FA exposure values were higher than indoor FA concentrations and the instructors (0.68, 0.04-2.11 ppm) had higher exposure than the students (0.44, 0.06-1.72 ppm). Unpleasant odor, eye and nose irritations and inability to concentrate were frequently reported FA-related symptoms, and the students were found to have significantly higher risks ( < 0.05) of having these symptoms during the dissection sessions than during lecture.

摘要

甲醛(FA)防腐法是世界上最常见的尸体固定方法,在缅甸的医科大学中一直被使用。本研究旨在检测解剖室(暴露场所)和演讲厅(非暴露对照场所)的室内 FA 浓度,并评估医学生和教师的 FA 个人暴露水平和临床症状。共有 208 名 2019 年入学的医学生(1/2019 批)和 18 名解剖学系教师参与了研究。2019 年 2 月至 2020 年 1 月,共调查了 13 次解剖课。扩散采样器被用作空气采样器,高效液相色谱法用于测量 FA。四个解剖室的平均室内 FA 浓度为 0.43(0.09-1.22)ppm,所有解剖室的室内浓度均高于职业暴露限值和一般人群的短期暴露限值。个人 FA 暴露值高于室内 FA 浓度,教师(0.68,0.04-2.11 ppm)的暴露值高于学生(0.44,0.06-1.72 ppm)。经常报告有不愉快的气味、眼睛和鼻子刺激以及注意力不集中等与 FA 相关的症状,而且学生在解剖课时比在演讲时更易出现这些症状(<0.05)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/6d6854bf6682/ijerph-18-00712-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/648d9d99a041/ijerph-18-00712-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/bb79ede32607/ijerph-18-00712-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/8f8d09c865df/ijerph-18-00712-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/4a0a3e5fdd14/ijerph-18-00712-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/3ab7a8dcf652/ijerph-18-00712-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/e55632cf9ee7/ijerph-18-00712-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/b3050584747a/ijerph-18-00712-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/e4c72fb04a97/ijerph-18-00712-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/6d6854bf6682/ijerph-18-00712-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/648d9d99a041/ijerph-18-00712-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/bb79ede32607/ijerph-18-00712-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/8f8d09c865df/ijerph-18-00712-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/4a0a3e5fdd14/ijerph-18-00712-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/3ab7a8dcf652/ijerph-18-00712-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/e55632cf9ee7/ijerph-18-00712-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/b3050584747a/ijerph-18-00712-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/e4c72fb04a97/ijerph-18-00712-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/7830549/6d6854bf6682/ijerph-18-00712-g009.jpg

相似文献

1
Indoor Formaldehyde Concentration, Personal Formaldehyde Exposure and Clinical Symptoms during Anatomy Dissection Sessions, University of Medicine 1, Yangon.仰光大学医学 1 分校解剖课期间的室内甲醛浓度、个人甲醛暴露与临床症状
Int J Environ Res Public Health. 2021 Jan 15;18(2):712. doi: 10.3390/ijerph18020712.
2
Formaldehyde exposure in a gross anatomy laboratory--personal exposure level is higher than indoor concentration.大体解剖实验室中的甲醛暴露——个人暴露水平高于室内浓度。
Environ Sci Pollut Res Int. 2006 Mar;13(2):120-4. doi: 10.1065/espr2005.06.265.
3
Formaldehyde exposure in gross anatomy laboratory of Suranaree University of Technology: a comparison of area and personal sampling.泰国苏兰拉里理工大学大体解剖实验室中的甲醛暴露:区域采样与个人采样的比较
Environ Sci Pollut Res Int. 2015 Dec;22(23):19002-12. doi: 10.1007/s11356-015-5078-2. Epub 2015 Aug 2.
4
Occupational exposure to formaldehyde in an institute of morphology in Brazil: a comparison of area and personal sampling.巴西形态学研究所中甲醛的职业暴露:区域采样与个体采样的比较。
Environ Sci Pollut Res Int. 2011 Aug;19(7):2813-9. doi: 10.1007/s11356-012-0786-3. Epub 2012 Feb 10.
5
Formaldehyde exposure of medical students and instructors and clinical symptoms during gross anatomy laboratory in Thammasat University.泰国国立法政大学大体解剖实验室中,医学生和教师接触甲醛的情况及临床症状。
J Med Assoc Thai. 2010 Dec;93 Suppl 7:S92-8.
6
[Formaldehyde concentrations in the breathing zone of medical students during gross anatomy laboratory in Toho University].[东京医科大学大体解剖实习中,医学生呼吸带的甲醛浓度]
Kaibogaku Zasshi. 2007 Jun;82(2):45-51.
7
Personal formaldehyde exposure level in the gross anatomy dissecting room at College of Medicine King Saud University Riyadh.沙特国王大学医学学院大体解剖实验室中个人甲醛暴露水平。
Int J Occup Med Environ Health. 2011 Mar;24(1):108-13. doi: 10.2478/s13382-011-0004-4. Epub 2011 Feb 16.
8
[Effect of large-scale repair work on indoor formaldehyde levels upon and subjective symptoms in, medical students during gross anatomy dissection course].[大规模维修工作对医学生大体解剖学课程期间室内甲醛水平及主观症状的影响]
Nihon Eiseigaku Zasshi. 2012;67(4):501-7. doi: 10.1265/jjh.67.501.
9
Evaluation of formaldehyde exposure among gross dissection after modified embalming solution and health assessment.改良防腐液处理后大体解剖过程中甲醛暴露情况评估及健康状况评价
Environ Sci Pollut Res Int. 2022 Sep;29(43):65642-65654. doi: 10.1007/s11356-022-19704-y. Epub 2022 Apr 30.
10
[Formaldehyde exposure levels and exposure control measures during an anatomy dissecting course].解剖学解剖课程中的甲醛暴露水平及暴露控制措施
Kaibogaku Zasshi. 2003 Jun;78(2):43-51.

引用本文的文献

1
Comparison of real-time instrument use and absorbent tube method for measuring formaldehyde in working environments: A health risk assessment for gross anatomy staff.工作环境中测量甲醛的实时仪器使用法与吸收管法的比较:大体解剖学工作人员的健康风险评估
Toxicol Rep. 2025 Jan 15;14:101913. doi: 10.1016/j.toxrep.2025.101913. eCollection 2025 Jun.
2
Antioxidants as Protection against Reactive Oxygen Stress Induced by Formaldehyde (FA) Exposure: A Systematic Review.抗氧化剂对甲醛暴露诱导的活性氧应激的防护作用:一项系统评价
Biomedicines. 2024 Aug 10;12(8):1820. doi: 10.3390/biomedicines12081820.
3
From hazard identification to risk assessment: The role of the prevention technician in the carcinogenic risk assessment for formaldehyde.

本文引用的文献

1
Low cost and effective reduction of formaldehyde in gross anatomy: long throw nozzles and formaldehyde destruction using InfuTrace™.降低大体解剖学甲醛用量的低成本有效方法:使用 InfuTrace™的长喷管和甲醛破坏。
Environ Sci Pollut Res Int. 2020 Dec;27(36):45189-45208. doi: 10.1007/s11356-020-09961-0. Epub 2020 Aug 11.
2
Recommendations of the working group of the Anatomische Gesellschaft on reduction of formaldehyde exposure in anatomical curricula and institutes.解剖学协会工作组关于减少解剖学课程及机构中甲醛暴露的建议。
Ann Anat. 2019 Jan;221:179-185. doi: 10.1016/j.aanat.2018.10.007. Epub 2018 Oct 25.
3
从危害识别到风险评估:预防技师在甲醛致癌风险评估中的作用。
Front Public Health. 2023 Apr 14;11:960921. doi: 10.3389/fpubh.2023.960921. eCollection 2023.
4
The Carcinogenic Effects of Formaldehyde Occupational Exposure: A Systematic Review.甲醛职业暴露的致癌作用:一项系统评价
Cancers (Basel). 2021 Dec 29;14(1):165. doi: 10.3390/cancers14010165.
5
Three-Dimensional Virtual Anatomy as a New Approach for Medical Student's Learning.三维虚拟解剖作为医学生学习的新方法。
Int J Environ Res Public Health. 2021 Dec 16;18(24):13247. doi: 10.3390/ijerph182413247.
6
Occupational Exposure to Formaldehyde and Cancer Risk Assessment in an Anatomy Laboratory.解剖实验室甲醛职业暴露与癌症风险评估。
Int J Environ Res Public Health. 2021 Oct 25;18(21):11198. doi: 10.3390/ijerph182111198.
Recommendation of Occupational Exposure Limits (2018-2019).
职业接触限值建议(2018 - 2019年)
J Occup Health. 2018;60(5):419-542. doi: 10.1539/joh.ROEL2018.
4
Levels of formaldehyde vapor released from embalmed cadavers in each dissection stage.从每个解剖阶段的防腐尸体中释放出的甲醛蒸气的水平。
Environ Sci Pollut Res Int. 2016 Aug;23(16):16176-82. doi: 10.1007/s11356-016-6744-8. Epub 2016 May 6.
5
Occupational exposure of a medical school staff to formaldehyde in tehran.德黑兰一所医学院工作人员的职业性甲醛暴露。
Tanaffos. 2012;11(3):36-41.
6
A toxicological investigation of lower aliphatic aldehydes. I. Toxicity of formaldehyde, acetaldehyde; propionaldehyde and butyraldehyde; as well as of acrolein and crotonaldehyde.低级脂肪醛的毒理学研究。I. 甲醛、乙醛、丙醛和丁醛以及丙烯醛和巴豆醛的毒性。
Acta Pharmacol Toxicol (Copenh). 1950;6(4):299-318. doi: 10.1111/j.1600-0773.1950.tb03477.x.
7
Indoor volatile organic compounds and chemical sensitivity reactions.室内挥发性有机化合物与化学敏感性反应。
Clin Dev Immunol. 2013;2013:623812. doi: 10.1155/2013/623812. Epub 2013 Oct 21.
8
Excruciating effect of formaldehyde exposure to students in gross anatomy dissection laboratory.大体解剖学解剖实验室中甲醛暴露对学生的极度影响。
Int J Occup Environ Med. 2012 Apr;3(2):92-5.
9
Ethanol-glycerin fixation with thymol conservation: a potential alternative to formaldehyde and phenol embalming.乙醇-甘油固定加百里香酚保存:一种替代福尔马林和苯酚防腐液的潜在方法。
Anat Sci Educ. 2012 Jul-Aug;5(4):225-33. doi: 10.1002/ase.1270. Epub 2012 Mar 20.
10
Potential health hazards for students exposed to formaldehyde in the gross anatomy laboratory.在大体解剖实验室中接触甲醛的学生所面临的潜在健康危害。
J Environ Health. 2012 Jan-Feb;74(6):36-40.