Department of Physiology, University of Medicine 1, Yangon 11014, Myanmar.
Faculty and Graduate School of Engineering, Chiba University, Chiba 263-8522, Japan.
Int J Environ Res Public Health. 2021 Jan 15;18(2):712. doi: 10.3390/ijerph18020712.
The formaldehyde (FA) embalming method, the world's most common protocol for the fixation of cadavers, has been consistently used in medical universities in Myanmar. This study was designed to examine the indoor FA concentrations in anatomy dissection rooms, an exposed site, and lecture theater, an unexposed control site, and to access personal exposure levels of FA and clinical symptoms of medical students and instructors. In total, 208 second year medical students (1/2019 batch) and 18 instructors from Department of Anatomy, University of Medicine 1, participated. Thirteen dissection sessions were investigated from February 2019 to January 2020. Diffusive sampling devices were used as air samplers and high-performance liquid chromatography was used for measurement of FA. Average indoor FA concentration of four dissection rooms was 0.43 (0.09-1.22) ppm and all dissection rooms showed indoor concentrations above the occupational exposure limits and short-term exposure limit for general population. Personal FA exposure values were higher than indoor FA concentrations and the instructors (0.68, 0.04-2.11 ppm) had higher exposure than the students (0.44, 0.06-1.72 ppm). Unpleasant odor, eye and nose irritations and inability to concentrate were frequently reported FA-related symptoms, and the students were found to have significantly higher risks ( < 0.05) of having these symptoms during the dissection sessions than during lecture.
甲醛(FA)防腐法是世界上最常见的尸体固定方法,在缅甸的医科大学中一直被使用。本研究旨在检测解剖室(暴露场所)和演讲厅(非暴露对照场所)的室内 FA 浓度,并评估医学生和教师的 FA 个人暴露水平和临床症状。共有 208 名 2019 年入学的医学生(1/2019 批)和 18 名解剖学系教师参与了研究。2019 年 2 月至 2020 年 1 月,共调查了 13 次解剖课。扩散采样器被用作空气采样器,高效液相色谱法用于测量 FA。四个解剖室的平均室内 FA 浓度为 0.43(0.09-1.22)ppm,所有解剖室的室内浓度均高于职业暴露限值和一般人群的短期暴露限值。个人 FA 暴露值高于室内 FA 浓度,教师(0.68,0.04-2.11 ppm)的暴露值高于学生(0.44,0.06-1.72 ppm)。经常报告有不愉快的气味、眼睛和鼻子刺激以及注意力不集中等与 FA 相关的症状,而且学生在解剖课时比在演讲时更易出现这些症状(<0.05)。