Department of Environmental Engineering and Occupational Safety and Health, Faculty of Technical Sciences, University of Novi Sad, 21000 Novi Sad, Serbia.
Department of Graphic Engineering and Design, Faculty of Technical Sciences, University of Novi Sad, 21000 Novi Sad, Serbia.
Int J Environ Res Public Health. 2021 Oct 25;18(21):11198. doi: 10.3390/ijerph182111198.
Dissecting a human cadaver is an irreplaceable practice in general training of medical students. Cadavers in anatomy laboratories are usually preserved in formalin, an embalming fluid whose basic component is formaldehyde (FA). The aim of this study is to assess the cancer risk of employees and students that are exposed to FA based on the results of three monitoring campaigns, as well as to suggest permanent solutions to the problem of FA exposure based on the results obtained. Three sampling campaigns of formaldehyde concentration in indoor environments were conducted at five different locations at the Anatomy Department of the Faculty of Medicine with the purpose of assessing permanent employees' and medical faculty first year students' exposure to FA. Indoor air was continuously sampled during 8 h of laboratory work and analyzed in accordance with the NIOSH Method 3500. Exceeding of the 8 h time-weighted average (8 h TWA) values recommended by Occupational Safety and Health Administration (OSHA) of 0.75 ppm was recorded in 37% of the samples during the three-month monitoring campaign. Cancer risk assessment levels for permanent employees were in the range from 6.43 × 10 to 8.77 × 10, while the cancer risk assessment levels for students ranged from 8.94 × 10 to 1.83 × 10. The results of the research show that cancer risk assessment for employees is several thousand times higher than the limit recommended by the EPA (10) and point to the importance of reducing exposure to formaldehyde through the reconstruction of the existing ventilation system, continual monitoring, the use of formaldehyde-free products, and plastination of anatomical specimens.
解剖人体尸体是医学生综合培训中不可或缺的实践。解剖实验室中的尸体通常保存在福尔马林中,福尔马林是一种防腐剂,其基本成分是甲醛(FA)。本研究旨在根据三次监测活动的结果评估接触 FA 的员工和学生的癌症风险,并根据所获得的结果提出解决 FA 暴露问题的永久解决方案。在医学院解剖系的五个不同地点进行了三次室内环境中甲醛浓度的抽样活动,目的是评估固定员工和医学系一年级学生接触 FA 的情况。在实验室工作的 8 小时内连续采集室内空气样本,并按照 NIOSH 方法 3500 进行分析。在三个月的监测活动中,有 37%的样本超过了职业安全与健康管理局(OSHA)推荐的 8 小时时间加权平均值(8 h TWA)值 0.75 ppm。固定员工的癌症风险评估水平在 6.43×10 到 8.77×10 之间,而学生的癌症风险评估水平在 8.94×10 到 1.83×10 之间。研究结果表明,员工的癌症风险评估比 EPA(10)推荐的限值高出数千倍,这表明通过重建现有通风系统、持续监测、使用无甲醛产品和标本塑化来减少甲醛暴露的重要性。