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忙碌日效应对产妇产时不良结局的影响:一项 601247 例单胎分娩的基于人群的研究。

Busy day effect on intrapartum adverse maternal outcomes - a population-based study of 601 247 singleton deliveries.

机构信息

Doctoral Programme in Clinical Research, Faculty of Medicine, University of Helsinki, Haartmanninkatu 8, 00290, Helsinki, Finland.

School of Health, Tampere University of Applied Sciences, Kuntokatu 3, 33520, Tampere, Finland.

出版信息

BMC Pregnancy Childbirth. 2021 Jan 19;21(1):66. doi: 10.1186/s12884-021-03552-8.

Abstract

BACKGROUND

This was a retrospective population-based study, utilizing the data of 601 247 singleton hospital deliveries collected from the Finnish Medical Birth Register (MBR) in 2006-2016. The aim of this study was to analyse the busy day effect on intrapartum adverse maternal outcomes.

METHODS

To implement the study design, daily delivery frequencies and ranges (min-max) for each delivery unit (n = 26) were stratified to the daily delivery volume distributions by the delivery unit's annual delivery volume and profile: Category (C)1 < 1000, C2 1000-1999, C3 2000-2999, C4 ≥ 3000 and C5 the profile of university hospitals. To study the busy day effect, the quiet, optimal and busy days were defined by calculating the number of days (%) with the lowest and highest daily delivery frequencies and summed to the nearest 10 % in each hospital category. Optimal days were determined by calculating approximately 80 % of deliveries occurring between the lowest 10 %, and highest 10 % in each hospital category. Crude and adjusted odd ratios (ORs) with 99 % confidence intervals (CIs) were used to analyze the busy day effect on adverse maternal outcomes, blood transfusions, manual removal of the placenta and obstetric anal sphincter injuries, separately in each hospital category.

RESULTS

The busy day effect was associated with the 28 % (99 % CI 8-52 %) and 25 % (99 % CI 11-40 %) increased need for blood transfusions in C2 and university hospitals (C5), respectively, whereas 22 % (99 % CI 10-31 %) less blood transfusions were needed at university hospitals during quiet days. In C3 hospitals, 83 % (99 % CI 65-92 %) less blood transfusions were needed during busy days. Obstetric and anal sphincter injury rates declined during quiet days by 22 % (99 % CI 3-38 %) only in university hospitals.

CONCLUSIONS

The findings of this study identify no specific pattern to the busy day effect for adverse maternal outcomes defined as manual removal of the placenta or obstetric and anal sphincter injuries. However, both quiet and busy days seem to be associated with increased or decreased need for blood transfusions in different sized delivery units. Findings also suggest that quiet days are associated with a decreased number of obstetric and anal sphincter injuries.

摘要

背景

这是一项回顾性的基于人群的研究,利用了芬兰医疗出生登记处(MBR)2006-2016 年期间收集的 601247 例单胎医院分娩数据。本研究的目的是分析产程中不良母婴结局的忙碌日效应。

方法

为了实施研究设计,根据分娩单位的年分娩量和特征,将每日分娩频率和范围(最小-最大)分层为每日分娩量分布:类别(C)1<1000、C21000-1999、C32000-2999、C4≥3000 和 C5大学医院的特征。为了研究忙碌日效应,通过计算每个医院类别中最低和最高每日分娩频率的天数(%)并将其舍入到最接近的 10%,定义了安静日、最佳日和忙碌日。最佳日是通过计算每个医院类别中最低 10%和最高 10%之间大约 80%的分娩来确定的。使用粗比值比(OR)和 99%置信区间(CI)分别分析了每个医院类别中不良母婴结局、输血、手动胎盘剥离和产科肛门括约肌损伤的忙碌日效应。

结果

忙碌日效应与 C2 医院(C5 大学医院)分别 28%(99%CI8-52%)和 25%(99%CI11-40%)的输血需求增加有关,而在安静日,C5 大学医院的输血需求减少了 22%(99%CI10-31%)。在 C3 医院,忙碌日的输血需求减少了 83%(99%CI65-92%)。只有在大学医院,安静日产科和肛门括约肌损伤率下降了 22%(99%CI3-38%)。

结论

本研究的结果表明,对于定义为手动胎盘剥离或产科和肛门括约肌损伤的不良母婴结局,没有特定的忙碌日效应模式。然而,在不同规模的分娩单位中,安静日和忙碌日似乎都与输血需求的增加或减少有关。研究结果还表明,安静日与产科和肛门括约肌损伤数量的减少有关。

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