Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Emory Critical Care Center, Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
J Racial Ethn Health Disparities. 2022 Apr;9(2):385-389. doi: 10.1007/s40615-021-00966-0. Epub 2021 Jan 19.
Studies of COVID-19 have shown that African Americans have been affected by the virus at a higher rate compared to other races. This cohort study investigated comorbidities and clinical outcomes by race among COVID-19 patients admitted to the intensive care unit.
This is a case series of critically ill patients admitted with COVID-19 to an academic healthcare system in Atlanta, Georgia. The study included all critically ill hospitalized patients between March 6, 2020, and May 5, 2020. Clinical outcomes during hospitalization included mechanical ventilation, renal replacement therapy, and mortality stratified by race.
Of 288 patients included (mean age, 63 ± 16 years; 45% female), 210 (73%) were African American. African Americans had significantly higher rates of comorbidities compared to other races, including hypertension (80% vs 59%, P = 0.001), diabetes (49% vs 34%, P = 0.026), and mean BMI (33 kg/m vs 28 kg/m, P < 0.001). Despite African Americans requiring continuous renal replacement therapy during hospitalization at higher rates than other races (27% vs 13%, P = 0.011), rates of intubation, intensive care unit length of stay, and overall mortality (30% vs 24%, P = 0.307) were similar.
This racially diverse series of critically ill COVID-19 patients shows that despite higher rates of comorbidities at hospital admission in African Americans compared with other races, there was no significant difference in mortality.
COVID-19 研究表明，与其他种族相比，非裔美国人受到该病毒的影响更高。本队列研究调查了入住重症监护病房的 COVID-19 患者的合并症和临床结局。
这是一项在佐治亚州亚特兰大的学术医疗系统中入住重症监护病房的 COVID-19 危重患者的病例系列研究。该研究包括 2020 年 3 月 6 日至 2020 年 5 月 5 日期间所有住院的危重患者。住院期间的临床结局包括机械通气、肾脏替代治疗和按种族分层的死亡率。
在 288 例纳入的患者中（平均年龄 63 ± 16 岁，45%为女性），210 例（73%）为非裔美国人。与其他种族相比，非裔美国人的合并症发生率明显更高，包括高血压（80%比 59%，P=0.001）、糖尿病（49%比 34%，P=0.026）和平均 BMI（33 kg/m 比 28 kg/m，P<0.001）。尽管非裔美国人在住院期间接受持续肾脏替代治疗的比例高于其他种族（27%比 13%，P=0.011），但插管率、重症监护病房住院时间和总体死亡率（30%比 24%，P=0.307）相似。
本项由不同种族的 COVID-19 危重患者组成的系列研究表明，尽管与其他种族相比，非裔美国人入院时合并症的发生率更高，但死亡率没有显著差异。
