大肠杆菌几种膜脂生物合成基因（fabC、fabB、gpsA、plsB）的进一步定位
Further mapping of several membrane lipid biosynthetic genes (fabC, fabB, gpsA, plsB) of Escherichia coli.
作者信息
Clark D, Cronan J E
出版信息
J Bacteriol. 1977 Nov;132(2):549-54. doi: 10.1128/jb.132.2.549-554.1977.
Abstract
New genetic mapping data on several loci involved in membrane lipid synthesis are reported. We demonstrated that the lesion designated fabC by Broekman and Hoeckstra (Mol. Gen. Genet. 124:65-67, 1975) is a fabB mutation. In the course of this work, the orientation of the pdxB and fabB loci was determined. The order of the loci is fabB pdxB purF. We also report cotransduction between the gpsA and cysE loci and show that the order of these markers is mtl cysE gpsA. Cotransduction between the plsB and kdgK loci was also sought. Despite extensive experiments, we were unable to detect cotransduction between these loci. In addition, we were unable to detect cotransduction among several markers in region 46 to 48 min of the map.
摘要
报道了几个参与膜脂合成的基因座的新遗传图谱数据。我们证明，Broekman和Hoeckstra（《分子遗传学和普通遗传学》124:65 - 67，1975）指定为fabC的损伤是fabB突变。在这项工作过程中，确定了pdxB和fabB基因座的方向。这些基因座的顺序是fabB pdxB purF。我们还报道了gpsA和cysE基因座之间的共转导，并表明这些标记的顺序是mtl cysE gpsA。我们也试图寻找plsB和kdgK基因座之间的共转导。尽管进行了大量实验，我们仍未能检测到这些基因座之间的共转导。此外，我们未能检测到图谱中46至48分钟区域内几个标记之间的共转导。
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