Paul H. Chook Department of Information Systems and Statistics, Baruch College, The City University of New York, New York, New York, USA.
Department of Statistics, George Mason University, Fairfax, Virginia, USA.
Stat Med. 2021 Apr 15;40(8):1989-2005. doi: 10.1002/sim.8884. Epub 2021 Jan 20.
This article introduces a flexible nonparametric approach for analyzing the association between covariates and power spectra of multivariate time series observed across multiple subjects, which we refer to as multivariate conditional adaptive Bayesian power spectrum analysis (MultiCABS). The proposed procedure adaptively collects time series with similar covariate values into an unknown number of groups and nonparametrically estimates group-specific power spectra through penalized splines. A fully Bayesian framework is developed in which the number of groups and the covariate partition defining the groups are random and fit using Markov chain Monte Carlo techniques. MultiCABS offers accurate estimation and inference on power spectra of multivariate time series with both smooth and abrupt dynamics across covariate by averaging over the distribution of covariate partitions. Performance of the proposed method compared with existing methods is evaluated in simulation studies. The proposed methodology is used to analyze the association between fear of falling and power spectra of center-of-pressure trajectories of postural control while standing in people with Parkinson's disease.
本文介绍了一种灵活的非参数方法,用于分析跨多个受试者观测的多元时间序列的协变量与功率谱之间的关联,我们称之为多元条件自适应贝叶斯功率谱分析(MultiCABS)。所提出的方法自适应地将具有相似协变量值的时间序列收集到未知数量的组中,并通过惩罚样条非参数估计组特定的功率谱。我们开发了一个完全贝叶斯框架,其中组的数量和定义组的协变量分区是随机的,并使用马尔可夫链蒙特卡罗技术进行拟合。MultiCABS 通过对协变量分区分布进行平均,为具有平滑和突变动力学的多元时间序列的功率谱提供了准确的估计和推断。在模拟研究中,比较了所提出的方法与现有方法的性能。所提出的方法学用于分析帕金森病患者站立时姿势控制的身体重心轨迹的恐惧跌倒与功率谱之间的关联。