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结合淀粉和胶原蛋白的细菌纤维素生物复合材料的开发及其性能评估。

Development of Bacterial Cellulose Biocomposites Combined with Starch and Collagen and Evaluation of Their Properties.

作者信息

Nunes Silmar Baptista, Hodel Katharine Valéria Saraiva, Sacramento Giulia da Costa, Melo Pollyana da Silva, Pessoa Fernando Luiz Pellegrini, Barbosa Josiane Dantas Viana, Badaró Roberto, Machado Bruna Aparecida Souza

机构信息

PPG GETEC, University Center SENAI CIMATEC, National Service of Industrial Learning, SENAI CIMATEC, Salvador 41650-010, Brazil.

SENAI Institute of Innovation (ISI) in Health Advanced Systems (CIMATEC ISI SAS), University Center SENAI/CIMATEC, SENAI CIMATEC, Salvador 41650-010, Brazil.

出版信息

Materials (Basel). 2021 Jan 19;14(2):458. doi: 10.3390/ma14020458.

Abstract

One of the major benefits of biomedicine is the use of biocomposites as wound dressings to help improve the treatment of injuries. Therefore, the main objective of this study was to develop and characterize biocomposites based on bacterial cellulose (BC) with different concentrations of collagen and starch and characterize their thermal, morphological, mechanical, physical, and barrier properties. In total, nine samples were produced with fixed amounts of glycerol and BC and variations in the amount of collagen and starch. The water activity (0.400-0.480), water solubility (12.94-69.7%), moisture (10.75-20.60%), thickness (0.04-0.11 mm), water vapor permeability (5.59-14.06 × 10 g·mm/m·h·Pa), grammage (8.91-39.58 g·cm), opacity (8.37-36.67 Abs 600 nm·mm), elongation (4.81-169.54%), and tensile strength (0.99-16.32 MPa) were evaluated and defined. In addition, scanning electron microscopy showed that adding biopolymers in the cellulose matrix made the surface compact, which also influenced the visual appearance. Thus, the performance of the biocomposites was directly influenced by their composition. The performance of the different samples obtained resulted in them having different potentials for application considering the injury type. This provides a solution for the ineffectiveness of traditional dressings, which is one of the great problems of the biomedical sector.

摘要

生物医学的主要优势之一是使用生物复合材料作为伤口敷料,以帮助改善损伤治疗。因此,本研究的主要目的是开发并表征基于细菌纤维素(BC)与不同浓度胶原蛋白和淀粉的生物复合材料,并表征其热性能、形态、力学、物理和阻隔性能。总共制备了九个样品,其中甘油和BC的量固定,胶原蛋白和淀粉的量有所变化。对水活性(0.400 - 0.480)、水溶性(12.94 - 69.7%)、水分(10.75 - 20.60%)、厚度(0.04 - 0.11毫米)、水蒸气透过率(5.59 - 14.06×10克·毫米/米·小时·帕)、定量(8.91 - 39.58克/平方厘米)、不透明度(8.37 - 36.67吸光度600纳米·毫米)、伸长率(4.81 - 169.54%)和拉伸强度(0.99 - 16.32兆帕)进行了评估和测定。此外,扫描电子显微镜显示,在纤维素基质中添加生物聚合物使表面致密,这也影响了视觉外观。因此,生物复合材料的性能直接受其组成影响。考虑到损伤类型,所获得的不同样品的性能导致它们具有不同的应用潜力。这为传统敷料的无效性提供了解决方案,而传统敷料的无效性是生物医学领域的重大问题之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f7f/7833372/03122d6ce65c/materials-14-00458-g001.jpg

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