Department of Clinical Hematology, Aditya Birla Memorial Hospital, Pune, India.
Department of Pathology, Aditya Birla Memorial Hospital, Pune, India.
Pediatr Blood Cancer. 2021 Apr;68(4):e28893. doi: 10.1002/pbc.28893. Epub 2021 Jan 23.
Cytopenias are common among neonates in neonatal intensive care units (NICU). Although, bone marrow aspirations (BMAs) are often performed as part of diagnostic workup, but trephine bone marrow biopsies (BMBs) have not been reported from living neonates. BMB is indispensable to accurately assess the cellularity and architecture. There is paucity of literature regarding the technique of BMB in neonates. In this report, for the first time, we describe trephine BMB from posterior superior iliac crest (PSIC) using 18-gauge BMA needle in six living neonates admitted to NICU where BMB findings helped in understanding the underlying mechanism and diagnosis of cytopenias.
新生儿重症监护病房 (NICU) 中的新生儿常出现细胞减少症。尽管骨髓抽吸术 (BMA) 通常作为诊断检查的一部分进行，但尚未有来自活产新生儿的环钻式骨髓活检 (BMB) 报道。BMB 对于准确评估细胞结构和架构是不可或缺的。关于新生儿 BMB 技术的文献很少。在本报告中，我们首次描述了在 NICU 收治的 6 名活产新生儿中使用 18 号 BMA 针从前上髂嵴 (PSIC) 进行环钻式 BMB，BMB 结果有助于了解细胞减少症的潜在机制和诊断。
