Weill Cornell at NewYork-Presbyterian, Department of Radiology, New York, NY, USA. Electronic address: https://twitter.com/NishiMehtaMD.
Weill Cornell at NewYork-Presbyterian, Department of Radiology, New York, NY, USA. Electronic address: https://twitter.com/RachelMSales43.
Clin Imaging. 2021 Jul;75:12-15. doi: 10.1016/j.clinimag.2021.01.016. Epub 2021 Jan 19.
With the recent U.S. Food and Drug Administration (FDA)-approval and rollout of the Pfizer-BioNTech and Moderna COVID-19 vaccines, it is important for radiologists to consider recent COVID-19 vaccination history as a possible differential diagnosis for patients with unilateral axillary adenopathy. Hyperplastic axillary nodes can be seen on sonography after any vaccination but are more common after a vaccine that evokes a strong immune response, such as the COVID-19 vaccine. As the differential of unilateral axillary adenopathy includes breast malignancy, it is crucial to both thoroughly evaluate the breast for primary malignancy and to elicit history of recent vaccination. As COVID-19 vaccines will soon be available to a larger patient population, radiologists should be familiar with the imaging features of COVID-19 vaccine induced hyperplastic adenopathy and its inclusion in a differential for unilateral axillary adenopathy. Short-term follow-up for unilateral axillary adenopathy in the setting of recent COVID-19 vaccination is an appropriate recommendation, in lieu of immediately performing potentially unnecessary and costly axillary lymph node biopsies.
随着最近美国食品和药物管理局（FDA）批准和推出辉瑞-生物技术公司和 Moderna 的 COVID-19 疫苗，放射科医生有必要将最近的 COVID-19 疫苗接种史作为单侧腋窝淋巴结病患者的可能鉴别诊断之一。在任何疫苗接种后，超声都可以看到淋巴结增生，但在引起强烈免疫反应的疫苗（如 COVID-19 疫苗）接种后更常见。由于单侧腋窝淋巴结病的鉴别诊断包括乳腺癌，因此彻底评估乳房是否存在原发性恶性肿瘤并询问近期接种疫苗的历史至关重要。随着 COVID-19 疫苗将很快提供给更多的患者人群，放射科医生应该熟悉 COVID-19 疫苗引起的淋巴结增生的影像学特征及其在单侧腋窝淋巴结病鉴别诊断中的应用。对于近期 COVID-19 疫苗接种后出现的单侧腋窝淋巴结病，建议进行短期随访，而不是立即进行潜在的不必要且昂贵的腋窝淋巴结活检。
