Melbourne Dental School, The University of Melbourne, Carlton, Victoria, Australia.
Multidisciplinary Department of Medical-Surgical and Dental Specialities, Oral and Maxillofacial Surgery Unit, Azienda Ospedaliero Universitaria University of Campania "Luigi Vanvitelli", Naples, Italy.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Apr;131(4):e95-e99. doi: 10.1016/j.oooo.2020.11.016. Epub 2020 Dec 8.
Chemosensory dysfunction has increasingly been reported in patients with coronavirus disease 2019 (COVID-19). Here, we document a case of a patient with taste and smell alterations as the only clinical manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In March 2020, a 36-year-old woman presented with self-reported hypogeusia/ageusia and hyposmia/anosmia in the absence of any respiratory symptom. The patient, who had no clinical and radiographic signs of sinusitis and was otherwise healthy, eventually had a positive test result for SARS-CoV-2. She did not develop any COVID-19-related symptoms throughout her 6-month follow up. Her self-reported chemosensory dysfunction lasted for 12 weeks. To the best of our knowledge, this is the first report that has accurately documented taste and smell alteration as the sole manifestation of COVID-19 in an otherwise healthy individual. Overall, analysis of current evidence supports the inclusion of gustatory and olfactory alterations as cardinal symptoms of COVID-19. Dentists' awareness of the diagnostic criteria for case definition of COVID-19 can facilitate early detection of the disease.
味觉和嗅觉障碍在新型冠状病毒肺炎（COVID-19）患者中越来越多地被报道。在这里，我们记录了一例味觉和嗅觉改变作为严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）感染唯一临床表现的病例。2020 年 3 月，一名 36 岁女性出现味觉减退/味觉丧失和嗅觉减退/嗅觉丧失，无任何呼吸道症状。该患者无鼻窦炎的临床和影像学迹象，身体健康，最终 SARS-CoV-2 检测结果呈阳性。在她的 6 个月随访期间，她没有出现任何与 COVID-19 相关的症状。她自我报告的化学感觉功能障碍持续了 12 周。据我们所知，这是首例准确记录味觉和嗅觉改变作为 COVID-19 在健康个体中唯一表现的报告。总的来说，对现有证据的分析支持将味觉和嗅觉改变纳入 COVID-19 的主要症状。牙医对 COVID-19 病例定义的诊断标准的认识可以促进疾病的早期发现。
