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感染新冠病毒的医护人员的嗅觉和味觉障碍

Olfactory and taste disorders in healthcare workers with COVID-19 infection.

作者信息

Villarreal Ithzel Maria, Morato Marta, Martínez-RuizCoello Mar, Navarro Andrés, Garcia-Chillerón Raimon, Ruiz Álvaro, de Almeida Isabella Vacallanos, Mazón Luis, Plaza Guillermo

机构信息

ENT Department, Hospital Universitario de Fuenlabrada, Universidad Rey Juan Carlos, Camino del Molino, 2, Fuenlabrada, 28942, Madrid, Spain.

Occupational Health Department, Hospital Universitario de Fuenlabrada, Madrid, Spain.

出版信息

Eur Arch Otorhinolaryngol. 2021 Jun;278(6):2123-2127. doi: 10.1007/s00405-020-06237-8. Epub 2020 Jul 28.

Abstract

PURPOSE

Severe acute respiratory syndrome caused by COVID-19 has spread globally for the last few months. Healthcare workers (HCW) are overexposed and infection rates are higher than in the rest of the population. Strict clinical assessment is paramount to detect suspicious cases. In this context, olfactory or taste dysfunction (OTD) appears as an early and frequent symptom. Evaluating its presence in early stages plays an important role nowadays.

METHODS

We performed a descriptive observational single-center study among 256 HCW at Hospital Universitario de Fuenlabrada affected by COVID-19 and confirmed using RT-PCR. A telephonic interview was performed, after obtaining oral informed consent.

RESULTS

OTD was present in up to 70% of the cases as an early symptom, including mild-to-severe cases. The extent of these sensory deficits lasted an average of 11 days. In 26% of the patients, these sensory alterations persisted for over a month.

CONCLUSION

OTD is reported as an early symptom among HCW with SARS-CoV-2 infection. Its strong association with test positivity is useful in the management of the infection and should be enough to indicate preventive isolation. We consider that OTD needs to be included in clinical screening questionnaires in HCW.

摘要

目的

由新型冠状病毒肺炎(COVID-19)引起的严重急性呼吸综合征在过去几个月里已在全球蔓延。医护人员(HCW)接触风险过高,感染率高于其他人群。严格的临床评估对于发现可疑病例至关重要。在此背景下,嗅觉或味觉功能障碍(OTD)表现为一种早期且常见的症状。如今,评估其在早期阶段的存在情况具有重要作用。

方法

我们在富恩拉夫拉达大学医院对256名受COVID-19影响并经逆转录聚合酶链反应(RT-PCR)确诊的医护人员进行了一项描述性观察单中心研究。在获得口头知情同意后进行了电话访谈。

结果

高达70%的病例中OTD作为早期症状出现,包括轻症和重症病例。这些感觉缺陷的程度平均持续11天。26%的患者中,这些感觉改变持续超过一个月。

结论

OTD被报告为感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的医护人员的早期症状。其与检测阳性的强关联在感染管理中有用,并且应足以指示进行预防性隔离。我们认为OTD需要纳入医护人员的临床筛查问卷中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58ec/7385204/1564a70c70c1/405_2020_6237_Fig1_HTML.jpg

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