Graduate School of Medicine, International University of Health and Welfare, Japan.
Faculty of Human Sciences, University of Tsukuba, Japan.
Ind Health. 2021 Mar 27;59(2):128-141. doi: 10.2486/indhealth.2020-0176. Epub 2021 Jan 23.
Although participatory workplace improvement programs are known to provide favorable effects on high stress occupations like nursing, no studies have confirmed its effect using biomarkers. The aim of this study was to determine whether a participatory workplace improvement program would decrease stress-related symptoms as evaluated by biomarkers and self-reported stress among hospital nurses. Three actions to alleviate job stress, which were determined through focus group interviews and voting, were undertaken for two months. A total of 31 female Japanese nurses underwent measurement of inflammatory markers, autonomic nervous activity (ANA), and perceived job stress (PJS) at three-time points; before the program (T1), within a week after the completion of the program (T2), and three months after the program (T3). A series of inflammatory markers (Interferon-γ, Interleukin (IL)-6, and IL-12/23p40) decreased significantly at T2, and IL-12/23p40 and IL-15 significantly decreased at T3 compared to T1, while ANA and PJS remained unchanged. Our participatory program exerted beneficial effects in reducing inflammatory responses, but not for ANA and PJS. Further investigations with a better study design, i.e., a randomized controlled trial, and a larger sample size are warranted to determine what exerted beneficial effects on inflammatory markers and why other outcomes remained unchanged.
虽然参与式工作场所改进计划已知对护理等高压力职业有有利影响,但没有研究使用生物标志物证实其效果。本研究旨在确定参与式工作场所改进计划是否会通过生物标志物和自我报告的压力来减轻医院护士的压力相关症状。通过焦点小组访谈和投票确定了三项缓解工作压力的措施,为期两个月。共有 31 名日本女性护士在三个时间点(计划前(T1)、计划完成后一周内(T2)和计划完成三个月后(T3))接受了炎症标志物、自主神经活动(ANA)和感知工作压力(PJS)的测量。一系列炎症标志物(干扰素-γ、白细胞介素(IL)-6 和 IL-12/23p40)在 T2 时显著降低,IL-12/23p40 和 IL-15 在 T3 时与 T1 相比显著降低,而 ANA 和 PJS 保持不变。我们的参与式计划在减轻炎症反应方面产生了有益的效果,但对 ANA 和 PJS 没有效果。需要进一步进行设计更好的研究,即随机对照试验和更大的样本量的研究,以确定哪些因素对炎症标志物产生了有益的影响,以及为什么其他结果保持不变。