Mahmud Nadim, Asch David A, Sung Jessica, Reitz Catherine, Coniglio Mary S, McDonald Caitlin, Bernard Donna, Mehta Shivan J
Division of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Leonard David Institute of Health Economics, University of Pennsylvania, Philadelphia.
JAMA Netw Open. 2021 Jan 4;4(1):e2034553. doi: 10.1001/jamanetworkopen.2020.34553.
Outpatient colonoscopy is important for colorectal cancer screening. However, nonadherence and poor bowel preparation are common.
To determine if an automated text messaging intervention with a focus on informational and reminder functions could improve attendance rates and bowel preparation quality for outpatient colonoscopy.
DESIGN, SETTING, AND PARTICIPANTS: This randomized clinical trial was conducted in an endoscopy center at an urban academic medical center. Adult patients scheduled for outpatient colonoscopy between January and September 2019 were enrolled by telephone call (early phase) or by automated text message (late phase). Data were analyzed from October 2019 to January 2020.
After enrollment, patients were randomized in a 1:1 ratio to usual care (ie, written instructions and nurse telephone call) or to the intervention (ie, usual care plus an automated series of 9 educational or reminder text messages in the week prior to scheduled colonoscopy).
The primary outcome was appointment attendance rate with good or excellent bowel preparation. Secondary outcomes included appointment attendance rate, bowel preparation quality (poor or inadequate, fair or adequate, and good or excellent), and cancellation lead time (in days).
Among 753 patients included and randomized in the trial (median [interquartile range] age, 56 [49-64] years; 364 [48.3%] men; 429 [57.2%] Black), 367 patients were randomized to the intervention group and 386 patients were randomized to the control group. There was no significant difference in the primary outcome between groups (patients attending appointments with good or excellent bowel preparation: intervention, 195 patients [53.1%]; control, 210 patients [54.4%]; P = .73), including when stratified by early or late phase enrollment groups. Similarly, there were no significant differences in secondary outcomes.
This randomized clinical trial found no significant difference in appointment attendance or bowel preparation quality with an automated text messaging intervention compared with the usual care control. Future work could optimize the content and delivery of text message interventions or identify patient subgroups that may benefit from this approach.
ClinicalTrials.gov Identifier: NCT03710213.
门诊结肠镜检查对结直肠癌筛查很重要。然而,不依从和肠道准备不佳的情况很常见。
确定以信息和提醒功能为重点的自动短信干预是否能提高门诊结肠镜检查的就诊率和肠道准备质量。
设计、地点和参与者:这项随机临床试验在一家城市学术医疗中心的内镜检查中心进行。2019年1月至9月安排进行门诊结肠镜检查的成年患者通过电话(早期阶段)或自动短信(后期阶段)进行招募。对2019年10月至2020年1月的数据进行了分析。
入组后,患者按1:1的比例随机分为常规护理组(即书面说明和护士电话)或干预组(即常规护理加上在预定结肠镜检查前一周自动发送的一系列9条教育或提醒短信)。
主要结局是肠道准备良好或优秀的预约就诊率。次要结局包括预约就诊率、肠道准备质量(差或不足、一般或充足、良好或优秀)以及取消提前期(天数)。
在纳入试验并随机分组的753例患者中(年龄中位数[四分位间距]为56[49 - 64]岁;男性364例[48.3%];黑人429例[57.2%]),367例患者被随机分配到干预组,386例患者被随机分配到对照组。两组之间的主要结局没有显著差异(肠道准备良好或优秀的就诊患者:干预组195例[53.1%];对照组210例[54.4%];P = 0.73),按早期或后期入组分层时也是如此。同样,次要结局也没有显著差异。
这项随机临床试验发现,与常规护理对照相比,自动短信干预在预约就诊率或肠道准备质量方面没有显著差异。未来的工作可以优化短信干预的内容和发送方式,或确定可能从这种方法中受益的患者亚组。
ClinicalTrials.gov标识符:NCT03710213。