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阿根廷科尔多瓦地区人冠状病毒 OC43 和 229E 的循环。

Circulation of human coronaviruses OC43 and 229E in Córdoba, Argentina.

机构信息

Instituto de Virología "Dr. J. M. Vanella", Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina.

Cátedra de Clínica Pediátrica, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina.

出版信息

Arch Virol. 2021 Mar;166(3):929-933. doi: 10.1007/s00705-020-04914-x. Epub 2021 Jan 25.

DOI:10.1007/s00705-020-04914-x
PMID:33492522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7829625/
Abstract

This is the first study of respiratory infections in Córdoba, Argentina, caused by endemic human coronavirus (HCoV)-OC43 and HCOV-229E, which circulated during 2011-2012 at a 3% rate, either as single or multiple infections. They were detected mainly in children, but HCoV-229E was also found in adults. HCoV-229E was detected in five out of 631 samples (0.8%), and HCoV-OC43 was found in 14 out of 631 (2.2%) samples. Clinical manifestations ranged from fever to respiratory distress, and a significant association of HCoV-229E with asthma was observed. Further studies and surveillance are needed to provide better clinical insights, early diagnosis, and medical care of patients, as well as to contribute to epidemiology modeling and prevention.

摘要

这是阿根廷科尔多瓦地区首次针对地方性人类冠状病毒（HCoV）-OC43 和 HCoV-229E 引起的呼吸道感染进行的研究。这些病毒在 2011 年至 2012 年期间以 3%的比例单独或混合感染，循环传播。它们主要在儿童中检测到，但也在成年人中发现了 HCoV-229E。在 631 个样本中，有 5 个（0.8%）检测到 HCoV-229E，14 个（2.2%）检测到 HCoV-OC43。临床表现从发热到呼吸窘迫不等，并且观察到 HCoV-229E 与哮喘之间存在显著关联。需要进一步的研究和监测，以提供更好的临床见解、早期诊断和医疗护理，并为流行病学模型和预防做出贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bab7/7829625/7f2ca867340f/705_2020_4914_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bab7/7829625/7f2ca867340f/705_2020_4914_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bab7/7829625/7f2ca867340f/705_2020_4914_Fig1_HTML.jpg

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