Choi Jeong-Woo, Yoon Jinho, Lim Joungpyo, Shin Minkyu, Lee Sang-Nam
Department of Chemical & Biomolecular Engineering, Sogang University, 35 Baekbeom-Ro, Mapo-Gu, Seoul 04107, Korea.
Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
Materials (Basel). 2021 Jan 21;14(3):518. doi: 10.3390/ma14030518.
Graphene has been studied a lot in different scientific fields because of its unique properties, including its superior conductivity, plasmonic property, and biocompatibility. More recently, transition metal dicharcogenide (TMD) nanomaterials, beyond graphene, have been widely researched due to their exceptional properties. Among the various TMD nanomaterials, molybdenum disulfide (MoS) has attracted attention in biological fields due to its excellent biocompatibility and simple steps for synthesis. Accordingly, graphene and MoS have been widely studied to be applied in the development of biosensors. Moreover, nanohybrid materials developed by hybridization of graphene and MoS have a huge potential for developing various types of outstanding biosensors, like electrochemical-, optical-, or surface-enhanced Raman spectroscopy (SERS)-based biosensors. In this review, we will focus on materials such as graphene and MoS. Next, their application will be discussed with regard to the development of highly sensitive biosensors based on graphene, MoS, and nanohybrid materials composed of graphene and MoS. In conclusion, this review will provide interdisciplinary knowledge about graphene/MoS nanohybrids to be applied to the biomedical field, particularly biosensors.
由于石墨烯具有独特的性质,包括卓越的导电性、等离子体特性和生物相容性,因此在不同的科学领域得到了广泛研究。最近,除石墨烯外,过渡金属二硫属化物(TMD)纳米材料因其优异的性能也受到了广泛研究。在各种TMD纳米材料中,二硫化钼(MoS)因其出色的生物相容性和简单的合成步骤而在生物领域引起了关注。因此,石墨烯和MoS已被广泛研究用于生物传感器的开发。此外,通过石墨烯和MoS杂交开发的纳米杂化材料在开发各种出色的生物传感器方面具有巨大潜力,如基于电化学、光学或表面增强拉曼光谱(SERS)的生物传感器。在本综述中,我们将重点关注石墨烯和MoS等材料。接下来,将讨论它们在基于石墨烯、MoS以及由石墨烯和MoS组成的纳米杂化材料开发高灵敏度生物传感器方面的应用。总之,本综述将提供有关石墨烯/MoS纳米杂化物的跨学科知识,以应用于生物医学领域,特别是生物传感器。