Alwhaibi Monira
Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11149, Saudi Arabia.
Medication Safety Research Chair, College of Pharmacy, King Saud University, Riyadh 11437, Saudi Arabia.
J Clin Med. 2024 Oct 10;13(20):6028. doi: 10.3390/jcm13206028.
Adults with type 2 diabetes are at a greater probability of suffering from mental health issues, which could result in a substantial effect on their HRQoL (health-related quality of life). Thus, the focus of this research was to investigate the relationship between comorbid anxiety, depression, and HRQoL among individuals with type 2 diabetes. Data from the Medical Expenditure Panel Survey from 2016 to 2021 were used to identify adult patients with type 2 diabetes diagnoses for this research. The MEPS used the SF-12 to measure HRQoL. The study employed multivariable linear regression to analyze the association between anxiety, depression, and HRQoL in individuals with type 2 diabetes, taking into consideration several confounding variables such as age, gender, and comorbidities. This study included 5259 individuals with type 2 diabetes, of which the mean age was 52.9 years, 50.7% were men, and 49.3% were women. The findings from this sample show a negative relationship between anxiety, depression, and type 2 diabetic patients' HRQoL. It shows that after adjusting for other factors, diabetes patients with depression (MCS: = -6.817), anxiety (MCS: = -4.957), and both (MCS: = -0.344) have a significantly poorer HRQoL than those without these mental health comorbidities (-value < 0.001). It also demonstrated the adverse effects on HRQoL of having coexisting chronic illnesses like heart disease, hypertension, and other chronic illnesses, along with a low socioeconomic status. Additionally, it revealed the benefits of employment, education, and regular exercise for HRQoL. The study's findings highlight the links between anxiety, depression, and type 2 diabetes patients' poor HRQoL. It also showed the adverse effects of coexisting chronic diseases and low socioeconomic status on HRQoL and the benefit of work and exercise on HRQoL. These findings can help policymakers to reform healthcare and enforce the early detection and treatment of anxiety and depression to enhance the HRQoL of type 2 diabetic patients.
2型糖尿病成人患者患心理健康问题的可能性更大，这可能会对他们的健康相关生活质量（HRQoL）产生重大影响。因此，本研究的重点是调查2型糖尿病患者中焦虑症、抑郁症与健康相关生活质量之间的关系。本研究使用了2016年至2021年医疗支出面板调查的数据来确定成年2型糖尿病患者。医疗支出面板调查使用SF-12来衡量健康相关生活质量。该研究采用多变量线性回归分析2型糖尿病患者中焦虑症、抑郁症与健康相关生活质量之间的关联，同时考虑年龄、性别和合并症等几个混杂变量。本研究纳入了5259名2型糖尿病患者，其中平均年龄为52.9岁，男性占50.7%，女性占49.3%。该样本的研究结果显示，焦虑症、抑郁症与2型糖尿病患者的健康相关生活质量之间存在负相关关系。结果表明，在调整其他因素后，患有抑郁症（心理综合得分：=-6.817）、焦虑症（心理综合得分：=-4.957）以及同时患有这两种疾病（心理综合得分：=-0.344）的糖尿病患者的健康相关生活质量明显低于没有这些心理健康合并症的患者（p值<0.001）。研究还表明，同时患有心脏病、高血压等慢性疾病以及社会经济地位较低会对健康相关生活质量产生不利影响。此外，研究还揭示了就业、教育和定期锻炼对健康相关生活质量的益处。该研究的结果突出了焦虑症、抑郁症与2型糖尿病患者健康相关生活质量低下之间的联系。研究还表明，并存的慢性疾病和低社会经济地位对健康相关生活质量有不利影响，而工作和锻炼对健康相关生活质量有益。这些研究结果可以帮助政策制定者改革医疗保健体系，并加强对焦虑症和抑郁症的早期检测和治疗，以提高2型糖尿病患者的健康相关生活质量。
