Penagini R, Al Dabbagh M, Misiewicz J J, Evans P F, Trotman I F
Department of Gastroenterology and Nutrition, Central Middlesex Hospital, London, England.
Dig Dis Sci. 1988 Apr;33(4):389-92. doi: 10.1007/BF01536019.
In 10 patients with peptic esophageal stricture the effect of esophageal dilatation on intraesophageal pH, stricture diameter, and dysphagia has been studied. Percentage of time during which intraesophageal pH was less than 4 and the number of reflux episodes per hour did not change significantly. Stricture diameter increased slightly, but consistently, from 7.0 +/- 0.5 mm to 9.1 +/- 0.5 mm (P less than 0.01) four days after dilatation, but was not significantly different from predilatation values after 12 weeks. Improvement in symptoms of dysphagia was striking (P less than 0.01) four days and six weeks after dilatation, but worsened again at 12 weeks (P = NS). It is unlikely that esophageal dilatation adversely affects the intraesophageal environment.
对10例消化性食管狭窄患者，研究了食管扩张术对食管内pH值、狭窄直径和吞咽困难的影响。食管内pH值低于4的时间百分比及每小时反流发作次数均无显著变化。扩张术后4天，狭窄直径从7.0±0.5毫米轻微但持续地增加至9.1±0.5毫米（P<0.01），但12周后与扩张前值无显著差异。扩张术后4天和6周吞咽困难症状改善显著（P<0.01），但12周时再次恶化（P=无显著性差异）。食管扩张术不太可能对食管内环境产生不利影响。
