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评价含五倍子提取物的正畸丙烯酸树脂的弯曲强度和抗菌效果。

Evaluation of flexural strength and antibacterial effect of orthodontic acrylic resins containing Galla chinensis extract.

机构信息

Shiraz University of Medical Sciences, Orthodontic Research Center, Dental School (Shiraz, Iran).

Shiraz University of Medical Sciences, School of Medicine, Department of Bacteriology and Virology (Shiraz, Iran).

出版信息

Dental Press J Orthod. 2020 Nov-Dec;25(6):43-48. doi: 10.1590/2177-6709.25.6.043-048.oar.

DOI:10.1590/2177-6709.25.6.043-048.oar
PMID:33503124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7869800/
Abstract

OBJECTIVE

To evaluate different concentrations of Galla chinensis extract (GCE) added to poly(methyl methacrylate) (PMMA), which is widely used for fabrication of removable orthodontic appliances, regarding the effectiveness of this herbal extract on antimicrobial effect and flexural strength of PMMA.

METHODS

Acrylic resin samples containing 0.4%, 0.8% and 1.6% GCE were prepared. Flexural strength was investigated via three-point flexural strength test for the 15 acrylic resin blocks of each concentration. Disk diffusion test was used to evaluate antibacterial effects of incorporating the same concentrations of GCE into acrylic resin. All these three groups were compared with the control group, with no added GCE, regarding flexural strength and antibacterial properties.

RESULTS

Comparison of flexural strength between the three study groups and the control group showed significant differences between the groups (P=0.018). However, there was no significant difference between the groups containing GCE. There were significant differences in antimicrobial activity between the four groups (P=0.026).

CONCLUSION

Within the limitations of this study, it is suggested that incorporation of GCE into PMMA would be beneficial for antimicrobial activity and flexural strength of PMMA, but further studies on other physical properties and antimicrobial effects on other bacterial strain would be beneficial prior to clinical investigations.

摘要

目的

评估不同浓度的五倍子提取物(GCE)添加到聚甲基丙烯酸甲酯(PMMA)中的效果,PMMA 广泛用于制作可摘正畸矫治器,考察这种草药提取物对 PMMA 的抗菌效果和弯曲强度的影响。

方法

制备含有 0.4%、0.8%和 1.6% GCE 的丙烯酸树脂样本。对每个浓度的 15 个丙烯酸树脂块进行三点弯曲强度试验,以研究弯曲强度。采用圆盘扩散试验评价将相同浓度的 GCE 掺入丙烯酸树脂中的抗菌效果。将这三组与不含 GCE 的对照组进行比较,比较其弯曲强度和抗菌性能。

结果

三组研究组与对照组的弯曲强度比较显示组间有显著差异(P=0.018)。然而,GCE 组之间没有显著差异。四组间的抗菌活性有显著差异(P=0.026)。

结论

在本研究的限制范围内,建议将 GCE 掺入 PMMA 中有益于提高 PMMA 的抗菌活性和弯曲强度,但在进行临床研究之前,需要进一步研究其他物理性能和对其他细菌菌株的抗菌效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8f1/7869800/48842801fb7b/2176-9451-dpjo-25-06-43-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8f1/7869800/48842801fb7b/2176-9451-dpjo-25-06-43-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8f1/7869800/48842801fb7b/2176-9451-dpjo-25-06-43-gf1.jpg

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