Charavet Carole, Graveline Léa, Gourdain Zoé, Lupi Laurence
Université Côte d'Azur, Faculté de Chirurgie Dentaire, 06800 Nice, France.
Centre Hospitalier Universitaire de Nice, Pôle Odontologie, 06000 Nice, France.
Children (Basel). 2021 Oct 26;8(11):967. doi: 10.3390/children8110967.
(1) Background: The use of removable orthodontic appliances, which is common in early ages, requires careful hygiene, as several different microorganisms are found on their surface during the orthodontic treatment. (2) Methods: Comprehensive electronic searches were conducted up to May 2021. Randomized controlled trials (RCTs) or controlled clinical trials (CCTs), prospective or retrospective, evaluating the efficacy of cleaning and disinfection methods for acrylic removable orthodontic appliances, redacted in the English language, were included. Three independent blinding review authors were involved in study selection, data extraction, and bias assessment. (3) Results: A total of 2491 records were screened and eight studies (six RCTs and two CCTs) fulfilled the inclusion criteria. Among the overall cleaning and disinfection methods described in the included studies, four categories could be defined: liquid antimicrobial agents, commercial tablet cleansers, natural plant extracts and incorporation of quaternary ammonium methacryloxy silicate, all of which demonstrated superior efficacy compared to the placebo/negative control. However, the different methods were not compared with each other. (4) Conclusions: Biofilm control on acrylic orthodontic removable appliances can be performed using the different cleaning and disinfection methods considered in the included studies. Further studies are needed to define the most effective technique. Registration: PROSPERO CRD 42021269297.
(1) 背景：可摘矫治器的使用在早期较为常见，由于在正畸治疗期间其表面发现有多种不同的微生物，因此需要仔细做好卫生清洁。(2) 方法：截至2021年5月进行了全面的电子检索。纳入以英文撰写的、评估丙烯酸类可摘矫治器清洁和消毒方法疗效的随机对照试验（RCT）或对照临床试验（CCT），前瞻性或回顾性研究均可。三位独立的盲法评审作者参与了研究选择、数据提取和偏倚评估。(3) 结果：共筛选了2491条记录，八项研究（六项RCT和两项CCT）符合纳入标准。在所纳入研究中描述的总体清洁和消毒方法中，可分为四类：液体抗菌剂、商用片剂清洁剂、天然植物提取物以及甲基丙烯酰氧基硅烷季铵盐的掺入，所有这些方法与安慰剂/阴性对照相比均显示出更好的疗效。然而，不同方法之间未进行相互比较。(4) 结论：可使用所纳入研究中考虑的不同清洁和消毒方法对丙烯酸类正畸可摘矫治器上的生物膜进行控制。需要进一步研究以确定最有效的技术。注册信息：PROSPERO CRD 42021269297。
