Laser Cutaneous Cosmetic & Plastic Surgery Unit, Villa Donatello Clinic, Florence, Italy.
Dermatol Ther. 2021 Mar;34(2):e14819. doi: 10.1111/dth.14819. Epub 2021 Feb 15.
Lasers are effective treatments for benign hyperpigmentations but may be difficult especially in darker skin type. In this randomized split-face controlled study on benign hyperpigmentations and pigmented scars, we compare the standard Single Pass (SP) emission with the MultiPass emission (MoveoPL) 755 alexandrite laser. Patients, skin types I-IV, with solar lentigines and ephelides of the face, chest, and hands and patients with pigmented scars of the legs, underwent laser treatment, by treating one side of the body or half scar using the SP and the other side using MoveoPL. Improvements according to a grading score system, side effects, and patient satisfaction were recorded. About 63 patients were enrolled. An overall improvement of benign hyperpigmentations and pigmented scars was recorded, with a grading score (±SD) of 2.8 ± 0.8 for SP and 3.6 ± 0.5 for MoveoPL (range, 0-4). SP emission showed best results in skin types I-II whereas MotusPL obtained successfully results in all the phototypes analyzed (types I-IV). Patients preferred MoveoPL as it was associated with fewer side effects. Both standard SP and MoveoPL emission are effective and safe. MoveoPL showed a higher efficacy and safety profile for the treatment of hyperpigmentations.
激光是治疗良性色素沉着的有效方法，但在深色皮肤类型中可能会比较困难。在这项关于良性色素沉着和色素性瘢痕的随机分面对照研究中，我们比较了标准的单次发射（SP）和多脉冲发射（MoveoPL）755 翠绿宝石激光。I-IV 型皮肤的患者，面部、胸部和手部有太阳斑和雀斑，腿部有色素性瘢痕，接受激光治疗，通过用 SP 治疗身体一侧或半条瘢痕，用 MoveoPL 治疗另一侧。根据分级评分系统、不良反应和患者满意度记录治疗效果。共纳入约 63 例患者。记录到良性色素沉着和色素性瘢痕的整体改善，SP 的分级评分（±SD）为 2.8±0.8，MoveoPL 为 3.6±0.5（范围，0-4）。SP 发射在 I-II 型皮肤中效果最好，而 MotusPL 在分析的所有肤色类型（I-IV）中都获得了成功的效果。患者更喜欢 MoveoPL，因为它的不良反应较少。标准 SP 和 MoveoPL 发射都有效且安全。MoveoPL 对色素沉着的治疗具有更高的疗效和安全性。
