Metabolomic profiling provides new insights into blood-brain barrier regulation.
作者信息
Huang Sheng-Fu, Ogunshola Omolara O
机构信息
Institute for Veterinary Physiology; Zurich Center for Integrative Human Physiology, University of Zurich, Switzerland.
出版信息
Neural Regen Res. 2021 Sep;16(9):1786-1787. doi: 10.4103/1673-5374.306077.
Abstract
摘要
相似文献
1
Metabolomic profiling provides new insights into blood-brain barrier regulation.代谢组学分析为血脑屏障调节提供了新的见解。
Neural Regen Res. 2021 Sep;16(9):1786-1787. doi: 10.4103/1673-5374.306077.
2
Cell-specific metabolomic responses to injury: novel insights into blood-brain barrier modulation.细胞特异性代谢组学对损伤的反应：血脑屏障调节的新见解。
Sci Rep. 2020 May 8;10(1):7760. doi: 10.1038/s41598-020-64722-w.
3
(1)H NMR studies distinguish the water soluble metabolomic profiles of untransformed and RAS-transformed cells.（1）核磁共振氢谱研究区分了未转化细胞和RAS转化细胞的水溶性代谢组学图谱。
PeerJ. 2016 Jun 7;4:e2104. doi: 10.7717/peerj.2104. eCollection 2016.
4
Identification of drug targets by chemogenomic and metabolomic profiling in yeast.通过酵母的化学生物组学和代谢组学分析鉴定药物靶点。
Pharmacogenet Genomics. 2012 Dec;22(12):877-86. doi: 10.1097/FPC.0b013e32835aa888.
5
The Effect of Blood Contained in the Samples on the Metabolomic Profile of Mouse Brain Tissue: A Study by NMR Spectroscopy.血液对小鼠脑组织代谢组学图谱的影响：NMR 光谱研究。
Molecules. 2021 May 22;26(11):3096. doi: 10.3390/molecules26113096.
6
Resolving coral photoacclimation dynamics through coupled photophysiological and metabolomic profiling.通过耦合光生理和代谢组学分析解析珊瑚的光驯化动态。
J Exp Biol. 2019 Apr 17;222(Pt 8):jeb195982. doi: 10.1242/jeb.195982.
7
Metabolomic profiling of neoplastic lesions in mice.小鼠肿瘤性病变的代谢组学分析
Methods Enzymol. 2014;543:261-73. doi: 10.1016/B978-0-12-801329-8.00013-1.
8
Transcriptomic and Gas Chromatography-Mass Spectrometry Metabolomic Profiling Analysis of the Epidermis Provides Insights into Cuticular Wax Regulation in Developing 'Yuluxiang' Pear Fruit.转录组和气相色谱-质谱代谢组学分析表皮为‘玉露香’梨果实发育过程中角质层蜡质的调控提供了新见解。
J Agric Food Chem. 2019 Jul 31;67(30):8319-8331. doi: 10.1021/acs.jafc.9b01899. Epub 2019 Jul 19.
9
Metabolomic Assessment of Key Maize Resources: GC-MS and NMR Profiling of Grain from B73 Hybrids of the Nested Association Mapping (NAM) Founders and of Geographically Diverse Landraces.基于巢式关联作图（NAM）的骨干自交系杂种 B73 及其地理起源不同的地方品种的籽粒代谢组学评估：GC-MS 和 NMR 分析
J Agric Food Chem. 2016 Mar 16;64(10):2162-72. doi: 10.1021/acs.jafc.5b04901. Epub 2016 Mar 7.
10
Pattern recognition approaches and computational systems tools for ultra performance liquid chromatography-mass spectrometry-based comprehensive metabolomic profiling and pathways analysis of biological data sets.基于超高效液相色谱-质谱联用的生物数据集代谢组学全谱分析和途径分析的模式识别方法和计算系统工具。
Anal Chem. 2012 Jan 3;84(1):428-39. doi: 10.1021/ac202828r. Epub 2011 Dec 19.
引用本文的文献
1
TGF-Beta Modulates the Integrity of the Blood Brain Barrier In Vitro, and Is Associated with Metabolic Alterations in Pericytes.转化生长因子-β在体外调节血脑屏障的完整性，并与周细胞的代谢改变有关。
Biomedicines. 2023 Jan 14;11(1):214. doi: 10.3390/biomedicines11010214.
本文引用的文献
1
Astrocyte glutathione maintains endothelial barrier stability.星形胶质细胞谷胱甘肽维持内皮细胞屏障稳定性。
Redox Biol. 2020 Jul;34:101576. doi: 10.1016/j.redox.2020.101576. Epub 2020 May 19.
2
Cell-specific metabolomic responses to injury: novel insights into blood-brain barrier modulation.细胞特异性代谢组学对损伤的反应：血脑屏障调节的新见解。
Sci Rep. 2020 May 8;10(1):7760. doi: 10.1038/s41598-020-64722-w.
3
Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues.脑内皮细胞是与年龄相关的循环线索的敏感传感器。
Cell Rep. 2020 Mar 31;30(13):4418-4432.e4. doi: 10.1016/j.celrep.2020.03.012.
4
Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module.在健康和疾病模型中分析小鼠脑内皮转录组，揭示了一个核心的血脑屏障功能障碍模块。
Nat Neurosci. 2019 Nov;22(11):1892-1902. doi: 10.1038/s41593-019-0497-x. Epub 2019 Oct 14.
5
A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells.人神经血管单元的连接式器官芯片模型揭示了内皮细胞和神经元细胞的代谢偶联。
Nat Biotechnol. 2018 Oct;36(9):865-874. doi: 10.1038/nbt.4226. Epub 2018 Aug 20.
6
Isolation and differential transcriptome of vascular smooth muscle cells and mid-capillary pericytes from the rat brain.从大鼠脑组织中分离血管平滑肌细胞和中小动脉周细胞，并进行差异转录组分析。
Sci Rep. 2018 Aug 16;8(1):12272. doi: 10.1038/s41598-018-30739-5.
7
Targeting angiogenic metabolism in disease.针对疾病中的血管生成代谢。
Science. 2018 Mar 23;359(6382):1335-1336. doi: 10.1126/science.aar5557.
8
Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface.星形胶质细胞远端突起中的翻译在胶质血管界面形成分子异质性。
Cell Discov. 2017 Mar 28;3:17005. doi: 10.1038/celldisc.2017.5. eCollection 2017.
9
Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy.抑制内皮细胞中的糖酵解激活剂PFKFB3可诱导肿瘤血管正常化、削弱转移并改善化疗。
Cancer Cell. 2016 Dec 12;30(6):968-985. doi: 10.1016/j.ccell.2016.10.006. Epub 2016 Nov 17.
10
Differential responses of blood-brain barrier associated cells to hypoxia and ischemia: a comparative study.血脑屏障相关细胞对缺氧和缺血的不同反应：一项比较研究。
Fluids Barriers CNS. 2015 Feb 17;12:4. doi: 10.1186/2045-8118-12-4.
Zotero 插件