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俾路支省少女维生素D水平的人口统计学差异与趋势

Demographic Differences and Trends of Vitamin D Levels Among the Teenaged Girls in Balochistan.

作者信息

Rehman Gulalai, Ahmad Hajra, Ddin Allau, Rind Habibullah, Kashif Seemin, Saleem Amna, Kakar Saliha, Zarak Muhammad Samsoor

机构信息

Nutrition, Balochistan Institute of Nephrology and Urology Quetta, Quetta, PAK.

Environmental Design, Health, and Nutritional Sciences, Allama Iqbal Open University, Islamabad, PAK.

出版信息

Cureus. 2020 Dec 28;12(12):e12335. doi: 10.7759/cureus.12335.

DOI:10.7759/cureus.12335
PMID:33520531
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7837651/
Abstract

Background Vitamin D is a vital micronutrient and plays a vital role in defining the bone mineral density of an individual. There are many factors that regulate the levels of vitamin D in our body. The deficiency in vitamin D leads to various complications, with the most important one weakening of bones. Adolescence defines the degree of bone mineral density, which reduces with the growing age in a gradual fashion. Methods The study was a cross-sectional study conducted in Zarghoon town, Quetta, Pakistan. A sample size of 142 was taken from urban and rural areas. Participants were adolescent girls falling in the age bracket of 13-18 years. The circulating level of 25-hydroxy vitamin D was assessed using the ELISA (enzyme-linked immunosorbent assay) technique. Data were analyzed with SPSS Version 20 (IBM Corp.). Results Overall, vitamin D deficiency was 32.4%, and 9.9 % of girls were found to be severely deficient, where the highest proportion belonged to urban samples. The prevalence rate of vitamin D insufficiency was 39.4%. The urban population had a higher prevalence of low levels of vitamin D. In urban respondents, 49.1% had an insufficient vitamin D level, 33.3% had a deficient vitamin D level, and 17.5% had a severely deficient vitamin D level. In rural respondents, 47.1% had normal vitamin D levels, 32.9% had insufficient vitamin D levels, 15.3% were deficient, and 4.7% were severely deficient. Conclusion It was concluded that vitamin D deficiency has a high prevalence among adolescent girls of school age. Additionally, it is more prevalent in urban areas than in rural areas.

摘要

背景

维生素D是一种至关重要的微量营养素,在确定个体的骨矿物质密度方面发挥着关键作用。有许多因素调节我们体内维生素D的水平。维生素D缺乏会导致各种并发症,其中最重要的是骨骼变弱。青春期决定了骨矿物质密度的程度,随着年龄的增长,骨矿物质密度会逐渐降低。

方法

该研究是在巴基斯坦奎达的扎尔贡镇进行的一项横断面研究。从城市和农村地区抽取了142个样本。参与者为年龄在13 - 18岁的青春期女孩。使用酶联免疫吸附测定(ELISA)技术评估25 - 羟基维生素D的循环水平。数据用SPSS 20版(IBM公司)进行分析。

结果

总体而言,维生素D缺乏率为32.4%,9.9%的女孩被发现严重缺乏,其中最高比例属于城市样本。维生素D不足的患病率为39.4%。城市人口中维生素D水平低的患病率更高。在城市受访者中,49.1%的人维生素D水平不足,33.3%的人维生素D缺乏,17.5%的人维生素D严重缺乏。在农村受访者中,47.1%的人维生素D水平正常,32.9%的人维生素D不足,15.3%的人维生素D缺乏,4.7%的人维生素D严重缺乏。

结论

得出的结论是,学龄期青春期女孩中维生素D缺乏的患病率很高。此外,城市地区比农村地区更普遍。

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The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention.维生素D缺乏大流行:诊断、治疗及预防方法
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Role of vitamin D in diabetes mellitus and chronic kidney disease.维生素D在糖尿病和慢性肾脏病中的作用。
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The Role of Vitamin D in Diabetes and Cardiovascular Disease: An Updated Review of the Literature.维生素D在糖尿病和心血管疾病中的作用:文献综述更新
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High prevalence of vitamin D deficiency and insufficiency in a low income peri-urban community in Karachi.卡拉奇低收入城郊社区维生素D缺乏和不足的高患病率。
J Pak Med Assoc. 2015 Sep;65(9):946-49.
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Vitamin D Actions on CD4(+) T Cells in Autoimmune Disease.维生素D在自身免疫性疾病中对CD4(+) T细胞的作用。
Front Immunol. 2015 Mar 18;6:100. doi: 10.3389/fimmu.2015.00100. eCollection 2015.
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Nat Rev Cancer. 2014 May;14(5):342-57. doi: 10.1038/nrc3691. Epub 2014 Apr 4.
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Presence of 25(OH) D deficiency in a rural North Indian village despite abundant sunshine.尽管阳光充足,但印度北部一个乡村仍存在25(OH)D缺乏的情况。
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