Bayle Catherine, Cantin Delphine, Vidal Jean-Sebastien, Sourdeau Elise, Slama Laurence, Dumesges Nicolas, Trombert Sabine, Ayllon Sonia, Nguyen Jean-Marie, Slama Dorsaf, Medaghecha Mohamed, Hanon Olivier, Salmon Dominique
Geriatry Department, Broca Hospital, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris Centre, Paris, France.
EA 4468, Université Paris Descartes, Paris, France.
Infect Dis Now. 2021 Mar;51(2):197-200. doi: 10.1016/j.idnow.2020.11.008. Epub 2021 Jan 18.
To show that circulation of SARS-COV-2 in nursing homes in France can come from staff as well as residents' families, whether they are known or not to have had COVID-19.
This study reports a screening campaign of asymptomatic staff working in elderly nursing homes in Paris where the virus had been circulating actively in March and April 2020.
Before the screening campaign, the rate of symptomatic COVID-19 was 23.3% among the residents and 12.1% among their home employees. Within a 72 h screening period, all employees not known to have the virus were screened by RT-PCR in nasopharyngeal swabs. Among the 241 screened employees, 32 (13.3%) tested positive for SARS-CoV-2 on RT-PCR. SARS-CoV-2 carriers and non-carriers did not differ in term of gender, age or type of staff. Staff carrying SARS-CoV-2 were strictly asymptomatic in 75% of cases while during the days following or before the test, 25% presented mild symptoms of COVID-19. Considering both symptomatic and asymptomatic cases, 66 out of 281 (23.5%) of the home employees had been carriers for COVID-19.
Screening for viral carriage of asymptomatic staff in nursing homes can avoid contact and transmission to frequently severely vulnerable residents.
证明在法国养老院中，严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的传播可能来自工作人员以及居民家属，无论他们是否已知感染过2019冠状病毒病（COVID-19）。
本研究报告了一项针对在巴黎老年养老院工作的无症状工作人员的筛查活动，2020年3月和4月期间该病毒在这些养老院中活跃传播。
在筛查活动之前，居民中出现症状的COVID-19感染率为23.3%，其家庭雇员中的感染率为12.1%。在72小时的筛查期内，所有未知感染病毒的雇员都接受了鼻咽拭子逆转录聚合酶链反应（RT-PCR）检测。在241名接受检测的雇员中，32人（13.3%）RT-PCR检测SARS-CoV-2呈阳性。SARS-CoV-2携带者和非携带者在性别、年龄或员工类型方面没有差异。75%的SARS-CoV-2携带者完全无症状，而在检测前或检测后的几天里，25%的人出现了COVID-19的轻微症状。综合有症状和无症状病例来看，281名家庭雇员中有66人（23.5%）曾是COVID-19携带者。
对养老院无症状工作人员进行病毒携带情况筛查可避免与通常极为脆弱的居民接触和传播。
