Lu Shiyu, Liu Tianyin, Wong Gloria H Y, Leung Dara K Y, Sze Lesley C Y, Kwok Wai-Wai, Knapp Martin, Lou Vivian W Q, Tse Samson, Ng Siu-Man, Wong Paul W C, Tang Jennifer Y M, Lum Terry Y S
Sau Po Centre on Ageing, The University of Hong Kong, Hong Kong, SAR, China.
Department of Social Work and Social Administration, The University of Hong Kong, Hong Kong, SAR, China.
Epidemiol Psychiatr Sci. 2021 Feb 2;30:e10. doi: 10.1017/S2045796020001122.
Late-life depression has substantial impacts on individuals, families and society. Knowledge gaps remain in estimating the economic impacts associated with late-life depression by symptom severity, which has implications for resource prioritisation and research design (such as in modelling). This study examined the incremental health and social care expenditure of depressive symptoms by severity.
We analysed data collected from 2707 older adults aged 60 years and over in Hong Kong. The Patient Health Questionnaire-9 (PHQ-9) and the Client Service Receipt Inventory were used, respectively, to measure depressive symptoms and service utilisation as a basis for calculating care expenditure. Two-part models were used to estimate the incremental expenditure associated with symptom severity over 1 year.
The average PHQ-9 score was 6.3 (standard deviation, s.d. = 4.0). The percentages of respondents with mild, moderate and moderately severe symptoms and non-depressed were 51.8%, 13.5%, 3.7% and 31.0%, respectively. Overall, the moderately severe group generated the largest average incremental expenditure (US$5886; 95% CI 1126-10 647 or a 272% increase), followed by the mild group (US$3849; 95% CI 2520-5177 or a 176% increase) and the moderate group (US$1843; 95% CI 854-2831, or 85% increase). Non-psychiatric healthcare was the main cost component in a mild symptom group, after controlling for other chronic conditions and covariates. The average incremental association between PHQ-9 score and overall care expenditure peaked at PHQ-9 score of 4 (US$691; 95% CI 444-939), then gradually fell to negative between scores of 12 (US$ - 35; 95% CI - 530 to 460) and 19 (US$ -171; 95% CI - 417 to 76) and soared to positive and rebounded at the score of 23 (US$601; 95% CI -1652 to 2854).
The association between depressive symptoms and care expenditure is stronger among older adults with mild and moderately severe symptoms. Older adults with the same symptom severity have different care utilisation and expenditure patterns. Non-psychiatric healthcare is the major cost element. These findings inform ways to optimise policy efforts to improve the financial sustainability of health and long-term care systems, including the involvement of primary care physicians and other geriatric healthcare providers in preventing and treating depression among older adults and related budgeting and accounting issues across services.
晚年抑郁症对个人、家庭和社会都有重大影响。在按症状严重程度评估与晚年抑郁症相关的经济影响方面,仍存在知识空白,这对资源优先排序和研究设计(如建模)具有重要意义。本研究考察了不同严重程度抑郁症状的额外健康和社会护理支出。
我们分析了从香港2707名60岁及以上老年人收集的数据。分别使用患者健康问卷-9(PHQ-9)和客户服务收据清单来测量抑郁症状和服务利用情况,作为计算护理支出的基础。采用两部分模型来估计1年内与症状严重程度相关的额外支出。
PHQ-9平均得分为6.3(标准差,s.d.=4.0)。症状轻微、中度、中度严重和无抑郁症状的受访者比例分别为51.8%、13.5%、3.7%和31.0%。总体而言,中度严重组产生的平均额外支出最大(5886美元;95%置信区间1,126 - 10,647美元,或增加272%),其次是轻度组(3849美元;95%置信区间2,520 - 5,177美元,或增加176%)和中度组(1843美元;95%置信区间854 - 2,8,31美元,或增加85%)。在控制其他慢性病和协变量后,非精神科医疗保健是轻度症状组的主要成本组成部分。PHQ-9得分与总体护理支出之间的平均额外关联在PHQ-9得分为4时达到峰值(691美元;95%置信区间444 - 939美元),然后在12分(-35美元;95%置信区间-530至460美元)和19分(-171美元;95%置信区间-417至76美元)之间逐渐降至负值,并在23分(601美元;95%置信区间-1,652至2,854美元)时飙升至正值并反弹。
在症状轻微和中度严重的老年人中,抑郁症状与护理支出之间的关联更强。症状严重程度相同的老年人有不同的护理利用和支出模式。非精神科医疗保健是主要成本要素。这些发现为优化政策努力提供了思路,以提高健康和长期护理系统的财务可持续性,包括让初级保健医生和其他老年医疗保健提供者参与预防和治疗老年人抑郁症以及跨服务的相关预算和会计问题。